FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2296784057> ?p ?o ?g. }

• W2296784057 endingPage "123" @default.
• W2296784057 startingPage "120" @default.
• W2296784057 abstract "Organophosphate (OP) poisoning is one of the most common causes of poisoning in developing countries especially in Southeastern Asia. Poisoning with phosphorus-containing organic chemicals or OP compounds can be managed with antidotes like oximes which are potential reactivators of acetylcholinesterase (AChE). The efficacy of oxime therapy in OP poisoned patients mainly depends upon various factors such as different dose plans, infusion rate of oximes, genetic differences of patients, type of oxime used and chemical nature of the OP compound ingested. Studies on pralidoxime kinetics in OP poisoned patients have shown that reactivation of AChE depends on the plasma concentration of oximes as well as OP compounds. The plasma concentration of oximes mainly depends on the dose plan from intermittent injection to continuous infusion after a loading dose. The incontrovertible fact is that the intermittent dosing of oximes results in deep troughs in blood pralidoxime/oxime levels (BPL) whereas continuous infusion of oximes maintains steady state plasma concentrations. Many published literature also highlighted pralidoxime via continuous infusion results in better outcomes with minimum fluctuation in BPL compared to intermittent dosing. At therapeutic doses, adverse effects of oximes are reported to be minimal. But high BPL is associated with some common adverse effects including dizziness, blurred vision and diastolic hypertension. Considering all the facts, it is important to note that kinetic studies of oximes are useful not only in deciding the dose regimen, but also in predicting the possible side-effects." @default.
• W2296784057 created "2016-06-24" @default.
• W2296784057 creator A5024510890 @default.
• W2296784057 creator A5029699553 @default.
• W2296784057 creator A5057384614 @default.
• W2296784057 creator A5074800193 @default.
• W2296784057 creator A5077919311 @default.
• W2296784057 creator A5081900212 @default.
• W2296784057 creator A5088928978 @default.
• W2296784057 date "2014-09-01" @default.
• W2296784057 modified "2023-10-03" @default.
• W2296784057 title "PHARMACOKINETIC STUDIES ON OXIMES IN ORGANOPHOSPHATE POISONING: A MINI REVIEW" @default.
• W2296784057 cites W1524864547 @default.
• W2296784057 cites W1539362429 @default.
• W2296784057 cites W1555390786 @default.
• W2296784057 cites W1716085683 @default.
• W2296784057 cites W1962039244 @default.
• W2296784057 cites W1986588490 @default.
• W2296784057 cites W1994766422 @default.
• W2296784057 cites W2004895379 @default.
• W2296784057 cites W2021704864 @default.
• W2296784057 cites W2030861170 @default.
• W2296784057 cites W2038600241 @default.
• W2296784057 cites W2038933848 @default.
• W2296784057 cites W2054746621 @default.
• W2296784057 cites W2060883036 @default.
• W2296784057 cites W2061103215 @default.
• W2296784057 cites W2096243864 @default.
• W2296784057 cites W2102561095 @default.
• W2296784057 cites W2135491682 @default.
• W2296784057 cites W2138702835 @default.
• W2296784057 cites W2142852307 @default.
• W2296784057 cites W2145028560 @default.
• W2296784057 cites W2161935966 @default.
• W2296784057 cites W2237604715 @default.
• W2296784057 cites W2285418350 @default.
• W2296784057 cites W2342600365 @default.
• W2296784057 cites W2417497599 @default.
• W2296784057 cites W2887928510 @default.
• W2296784057 cites W95229539 @default.
• W2296784057 cites W1861597347 @default.
• W2296784057 doi "https://doi.org/10.22038/apjmt.2014.3381" @default.
• W2296784057 hasPublicationYear "2014" @default.
• W2296784057 type Work @default.
• W2296784057 sameAs 2296784057 @default.
• W2296784057 citedByCount "2" @default.
• W2296784057 countsByYear W22967840572014 @default.
• W2296784057 countsByYear W22967840572015 @default.
• W2296784057 crossrefType "journal-article" @default.
• W2296784057 hasAuthorship W2296784057A5024510890 @default.
• W2296784057 hasAuthorship W2296784057A5029699553 @default.
• W2296784057 hasAuthorship W2296784057A5057384614 @default.
• W2296784057 hasAuthorship W2296784057A5074800193 @default.
• W2296784057 hasAuthorship W2296784057A5077919311 @default.
• W2296784057 hasAuthorship W2296784057A5081900212 @default.
• W2296784057 hasAuthorship W2296784057A5088928978 @default.
• W2296784057 hasConcept C112705442 @default.
• W2296784057 hasConcept C126322002 @default.
• W2296784057 hasConcept C161176658 @default.
• W2296784057 hasConcept C181199279 @default.
• W2296784057 hasConcept C185592680 @default.
• W2296784057 hasConcept C197934379 @default.
• W2296784057 hasConcept C2776327929 @default.
• W2296784057 hasConcept C2776588719 @default.
• W2296784057 hasConcept C2777288759 @default.
• W2296784057 hasConcept C2778736120 @default.
• W2296784057 hasConcept C2778816929 @default.
• W2296784057 hasConcept C2779648554 @default.
• W2296784057 hasConcept C2781413609 @default.
• W2296784057 hasConcept C27924281 @default.
• W2296784057 hasConcept C33070731 @default.
• W2296784057 hasConcept C42219234 @default.
• W2296784057 hasConcept C55493867 @default.
• W2296784057 hasConcept C6557445 @default.
• W2296784057 hasConcept C71924100 @default.
• W2296784057 hasConcept C86803240 @default.
• W2296784057 hasConcept C98274493 @default.
• W2296784057 hasConceptScore W2296784057C112705442 @default.
• W2296784057 hasConceptScore W2296784057C126322002 @default.
• W2296784057 hasConceptScore W2296784057C161176658 @default.
• W2296784057 hasConceptScore W2296784057C181199279 @default.
• W2296784057 hasConceptScore W2296784057C185592680 @default.
• W2296784057 hasConceptScore W2296784057C197934379 @default.
• W2296784057 hasConceptScore W2296784057C2776327929 @default.
• W2296784057 hasConceptScore W2296784057C2776588719 @default.
• W2296784057 hasConceptScore W2296784057C2777288759 @default.
• W2296784057 hasConceptScore W2296784057C2778736120 @default.
• W2296784057 hasConceptScore W2296784057C2778816929 @default.
• W2296784057 hasConceptScore W2296784057C2779648554 @default.
• W2296784057 hasConceptScore W2296784057C2781413609 @default.
• W2296784057 hasConceptScore W2296784057C27924281 @default.
• W2296784057 hasConceptScore W2296784057C33070731 @default.
• W2296784057 hasConceptScore W2296784057C42219234 @default.
• W2296784057 hasConceptScore W2296784057C55493867 @default.
• W2296784057 hasConceptScore W2296784057C6557445 @default.
• W2296784057 hasConceptScore W2296784057C71924100 @default.
• W2296784057 hasConceptScore W2296784057C86803240 @default.
• W2296784057 hasConceptScore W2296784057C98274493 @default.

• next