Matches in SemOpenAlex for { <https://semopenalex.org/work/W2296910028> ?p ?o ?g. }
- W2296910028 endingPage "514xs" @default.
- W2296910028 startingPage "508" @default.
- W2296910028 abstract "This is an update on skeletal muscle sodium channelopathies since knowledge in the field have dramatically increased in the past years.The relationship between two phenotypes and SCN4A has been confirmed with additional cases that remain extremely rare: severe neonatal episodic laryngospasm mimicking encephalopathy, which should be actively searched for since patients respond well to sodium channel blockers; congenital myasthenic syndromes, which have the particularity to be the first recessive Nav1.4 channelopathy. Deep DNA sequencing suggests the contribution of other ion channels in the clinical expressivity of sodium channelopathies, which may be one of the factors modulating the latter. The increased knowledge of channel molecular structure, the quantity of sodium channel blockers, and the availability of preclinical models would permit a most personalized choice of medication for patients suffering from these debilitating neuromuscular diseases.Advances in the understanding of the molecular structure of voltage-gated sodium channels, as well as availability of preclinical models, would lead to improved medical care of patients suffering from skeletal muscle, as well as other sodium channelopathies." @default.
- W2296910028 created "2016-06-24" @default.
- W2296910028 creator A5049997386 @default.
- W2296910028 creator A5062355834 @default.
- W2296910028 date "2015-10-01" @default.
- W2296910028 modified "2023-10-09" @default.
- W2296910028 title "Skeletal muscle sodium channelopathies" @default.
- W2296910028 cites W1504047759 @default.
- W2296910028 cites W1945545021 @default.
- W2296910028 cites W1963891743 @default.
- W2296910028 cites W1971567084 @default.
- W2296910028 cites W1978299298 @default.
- W2296910028 cites W1978389341 @default.
- W2296910028 cites W1986150601 @default.
- W2296910028 cites W1988441643 @default.
- W2296910028 cites W1991338743 @default.
- W2296910028 cites W1998078867 @default.
- W2296910028 cites W2001282076 @default.
- W2296910028 cites W2011683030 @default.
- W2296910028 cites W2017099242 @default.
- W2296910028 cites W2020448043 @default.
- W2296910028 cites W2024473147 @default.
- W2296910028 cites W2027780707 @default.
- W2296910028 cites W2035858511 @default.
- W2296910028 cites W2045139512 @default.
- W2296910028 cites W2052948802 @default.
- W2296910028 cites W2054058473 @default.
- W2296910028 cites W2056531158 @default.
- W2296910028 cites W2073452482 @default.
- W2296910028 cites W2078589887 @default.
- W2296910028 cites W2080940292 @default.
- W2296910028 cites W2081912246 @default.
- W2296910028 cites W2084235009 @default.
- W2296910028 cites W2086701162 @default.
- W2296910028 cites W2090682497 @default.
- W2296910028 cites W2091080398 @default.
- W2296910028 cites W2093309387 @default.
- W2296910028 cites W2096403728 @default.
- W2296910028 cites W2104415321 @default.
- W2296910028 cites W2104689137 @default.
- W2296910028 cites W2105806128 @default.
- W2296910028 cites W2108584860 @default.
- W2296910028 cites W2110896154 @default.
- W2296910028 cites W2113646199 @default.
- W2296910028 cites W2117672807 @default.
- W2296910028 cites W2119278180 @default.
- W2296910028 cites W2129396168 @default.
- W2296910028 cites W2136320182 @default.
- W2296910028 cites W2141124826 @default.
- W2296910028 cites W2146829251 @default.
- W2296910028 cites W2147699570 @default.
- W2296910028 cites W2152695330 @default.
- W2296910028 cites W2157594949 @default.
- W2296910028 cites W2158890341 @default.
- W2296910028 cites W2160142455 @default.
- W2296910028 cites W2163151214 @default.
- W2296910028 cites W2163706259 @default.
- W2296910028 cites W2166388246 @default.
- W2296910028 cites W2167192190 @default.
- W2296910028 cites W2169714889 @default.
- W2296910028 cites W2169894910 @default.
- W2296910028 cites W39959066 @default.
- W2296910028 doi "https://doi.org/10.1097/wco.0000000000000238" @default.
- W2296910028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26285000" @default.
- W2296910028 hasPublicationYear "2015" @default.
- W2296910028 type Work @default.
- W2296910028 sameAs 2296910028 @default.
- W2296910028 citedByCount "25" @default.
- W2296910028 countsByYear W22969100282015 @default.
- W2296910028 countsByYear W22969100282016 @default.
- W2296910028 countsByYear W22969100282017 @default.
- W2296910028 countsByYear W22969100282018 @default.
- W2296910028 countsByYear W22969100282019 @default.
- W2296910028 countsByYear W22969100282020 @default.
- W2296910028 countsByYear W22969100282021 @default.
- W2296910028 countsByYear W22969100282023 @default.
- W2296910028 crossrefType "journal-article" @default.
- W2296910028 hasAuthorship W2296910028A5049997386 @default.
- W2296910028 hasAuthorship W2296910028A5062355834 @default.
- W2296910028 hasBestOaLocation W22969100282 @default.
- W2296910028 hasConcept C118552586 @default.
- W2296910028 hasConcept C126322002 @default.
- W2296910028 hasConcept C178790620 @default.
- W2296910028 hasConcept C185592680 @default.
- W2296910028 hasConcept C2776414672 @default.
- W2296910028 hasConcept C2777989426 @default.
- W2296910028 hasConcept C2778186239 @default.
- W2296910028 hasConcept C2778621155 @default.
- W2296910028 hasConcept C2779959927 @default.
- W2296910028 hasConcept C2780623815 @default.
- W2296910028 hasConcept C50952357 @default.
- W2296910028 hasConcept C537181965 @default.
- W2296910028 hasConcept C60644358 @default.
- W2296910028 hasConcept C71924100 @default.
- W2296910028 hasConcept C86803240 @default.
- W2296910028 hasConceptScore W2296910028C118552586 @default.
- W2296910028 hasConceptScore W2296910028C126322002 @default.
- W2296910028 hasConceptScore W2296910028C178790620 @default.