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- W2296920437 abstract "Chronic alcohol use can result in structural and functional abnormalities in the brain. These changes are aggravated with nutritional deficiencies like thiamine deficiency. Advances in neuroimaging and quantitative studies have contributed significantly to the understanding of these neuropathological mechanisms underlying brain damage. This chapter focuses on the relationship between alcohol misuse and neuropsychiatric disorders. In addition, emphasis is given to the effects of alcohol on neurotransmitters and neuroregulatory hormones. Common syndromes discussed are Wernicke encephalopathy, Korsakoff syndrome, and alcohol withdrawal syndrome. Other disorders are alcohol-related dementia, alcoholic cerebellar degeneration, and alcoholic hallucinosis. Rarer diseases like Marchiafava–Bignami disease and central pontine myelinolysis have also been described. Early identification of potentially reversible pathological changes with studies on risk factors are tools that can be incorporated into public education programs. More research in preventive approaches is needed to help reduce the morbidity and mortality associated with this global health problem." @default.
- W2296920437 created "2016-06-24" @default.
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- W2296920437 date "2016-01-01" @default.
- W2296920437 modified "2023-09-27" @default.
- W2296920437 title "Neuropathology in Neuropsychiatric Disorders Secondary to Alcohol Misuse" @default.
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- W2296920437 doi "https://doi.org/10.1016/b978-0-12-800213-1.00058-4" @default.
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