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• W2296933152 startingPage "4159" @default.
• W2296933152 abstract "We report here that specific T-cell receptor rearrangements were observed in fractionated-X-irradiation-induced murine leukemias. Consistent gamma-chain rearrangements, limited beta-chain rearrangements, and no detectable alpha-chain rearrangements were observed. Gene expression studies revealed that, in comparison with normal thymus tissue, expression of alpha T-cell receptor genes was lower in the thymomas, beta expression was much higher but approximately equal to that of normal thymocytes, and gamma expression was significantly increased. After coupling these data with those from analyses using reagents against other surface markers, such as Lyt-2, L3T4, H-2, IL-2R and MEL-14, we concluded that the target T cells for fractionated-X-irradiation-induced transformation resemble fetal thymocytes from days 15 and 16 of gestation." @default.
• W2296933152 created "2016-06-24" @default.
• W2296933152 creator A5018286718 @default.
• W2296933152 creator A5002431996 @default.
• W2296933152 date "1987-12-01" @default.
• W2296933152 modified "2023-10-17" @default.
• W2296933152 title "Murine thymomas induced by fractionated-X-irradiation have specific T-cell receptor rearrangements and characteristics associated with day-15 to -16 fetal thymocytes." @default.
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• W2296933152 doi "https://doi.org/10.1128/mcb.7.12.4159" @default.
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