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- W2297069214 abstract "The discovery of the first giant virus, Mimivirus, in 2003 could solely have been that of an exceptional freak, a blind alley of evolution as occasionally encountered in biology, albeit without conceptual significance. On the contrary, once broken this epistemological barrier, additional unrelated families of giant viruses such as the Pandoraviruses, the Pithoviruses and most recently Mollivirus, were quickly unraveled, suggesting that an entire chapter of microbiology had been ignored since Pasteur and Ivanovski. In this article, we examine to what extent the giant viruses challenge previous definitions of viruses, the diversity of forms they could take, and how they might have evolved from extinct ancestral cellular lineages. Inspired by the epistemology of Gaston Bachelard, we will also suggest the reasons for which giant viruses laid hidden in plain sight for more than a century. Finally, we propose a new definition for viruses that paradoxically emphasize the fact that they do not encode a single universally shared macromolecule or biochemical function." @default.
- W2297069214 created "2016-06-24" @default.
- W2297069214 creator A5057768395 @default.
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- W2297069214 date "2016-10-01" @default.
- W2297069214 modified "2023-09-25" @default.
- W2297069214 title "Giant viruses: The difficult breaking of multiple epistemological barriers" @default.
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- W2297069214 doi "https://doi.org/10.1016/j.shpsc.2016.02.015" @default.
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