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- W2297100503 abstract "The innate immune system possesses a multitude of pathways to sense and respond to microbial pathogens. One such family are the interferons (IFNs), a family of cytokines that are involved in several cellular functions. Type I IFNs are appreciated to be important in several viral and bacterial diseases, while the recently identified type III IFNs (IFNL1, IFNL2, IFNL3, IFNL4) have been studied primarily in the context of viral infection. Viral and bacterial infections however are not mutually exclusive, and often the presence of a viral pathogen increases the pathogenesis of bacterial infection. The role of type III IFN in bacterial and viral-bacterial co-infections has just begun to be explored. In this mini review we discuss type III IFN signaling and its role in microbial pathogenesis with an emphasis on the work that has been conducted with bacterial pathogens." @default.
- W2297100503 created "2016-06-24" @default.
- W2297100503 creator A5015269643 @default.
- W2297100503 creator A5034101434 @default.
- W2297100503 date "2016-06-01" @default.
- W2297100503 modified "2023-09-27" @default.
- W2297100503 title "Microbial pathogenesis and type III interferons" @default.
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- W2297100503 doi "https://doi.org/10.1016/j.cytogfr.2016.02.005" @default.
- W2297100503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4899229" @default.
- W2297100503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26987613" @default.
- W2297100503 hasPublicationYear "2016" @default.
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