FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2297187856> ?p ?o ?g. }

• W2297187856 abstract "Correlated imaging of phosphorescence and fluorescence lifetime parameters of metabolic markers is a challenge for direct investigating mechanisms related to cell metabolism and oxygen tension. A large variety of clinical phenotypes is associated with mitochondrial defects accomplished with changes in cell metabolism. In many cases the hypoxic microenvironment of cancer cells shifts metabolism from oxidative phosphorylation (OXPHOS) to anaerobic or aerobic glycolysis, a process known as Warburg effect. Also during stem cell differentiation a switch in cell metabolism is observed. A defective mitochondrial function associated with hypoxia has been invoked in many complex disorders such as type 2 diabetes, Alzheimers disease, cardiac ischemia/reperfusion injury, tissue inflammation and cancer. Cellular responses to oxygen tension have been studied extensively, optical imaging techniques based on time correlated single photon counting (TCSPC) to detect the underlying metabolic mechanisms are therefore of prominent interest. They offer the possibility by inspecting fluorescence decay characteristics of intrinsic coenzymes to directly image metabolic pathways. Moreover oxygen tension can be determined by considering the phosphorescence lifetime of a phosphorescent probe. The combination of both fluorescence lifetime imaging (FLIM) of coenzymes like NADH and FAD and phosphorescence lifetime (PLIM) of phosphorescent dyes could provide valuable information about correlation of metabolic pathways and oxygen tension." @default.
• W2297187856 created "2016-06-24" @default.
• W2297187856 creator A5008248756 @default.
• W2297187856 creator A5050478637 @default.
• W2297187856 creator A5088830106 @default.
• W2297187856 date "2016-03-14" @default.
• W2297187856 modified "2023-09-26" @default.
• W2297187856 title "Correlated FLIM and PLIM for cell metabolism" @default.
• W2297187856 cites W1611437588 @default.
• W2297187856 cites W1979809444 @default.
• W2297187856 cites W1983199304 @default.
• W2297187856 cites W1984060145 @default.
• W2297187856 cites W1986163455 @default.
• W2297187856 cites W1989358149 @default.
• W2297187856 cites W2018056590 @default.
• W2297187856 cites W2019549478 @default.
• W2297187856 cites W2025568741 @default.
• W2297187856 cites W2029436635 @default.
• W2297187856 cites W2030831206 @default.
• W2297187856 cites W2033970221 @default.
• W2297187856 cites W2041060053 @default.
• W2297187856 cites W2047404221 @default.
• W2297187856 cites W2048151651 @default.
• W2297187856 cites W2059307385 @default.
• W2297187856 cites W2063910480 @default.
• W2297187856 cites W2067410660 @default.
• W2297187856 cites W2072451938 @default.
• W2297187856 cites W2078091226 @default.
• W2297187856 cites W2083147890 @default.
• W2297187856 cites W2084037323 @default.
• W2297187856 cites W2088341766 @default.
• W2297187856 cites W2101967659 @default.
• W2297187856 cites W2111920179 @default.
• W2297187856 cites W2117998556 @default.
• W2297187856 cites W2119795324 @default.
• W2297187856 cites W2121388227 @default.
• W2297187856 cites W2125852814 @default.
• W2297187856 cites W2129827453 @default.
• W2297187856 cites W2129995310 @default.
• W2297187856 cites W2135449908 @default.
• W2297187856 cites W2411893017 @default.
• W2297187856 cites W2485624919 @default.
• W2297187856 cites W2488383433 @default.
• W2297187856 cites W4230163636 @default.
• W2297187856 cites W4249171878 @default.
• W2297187856 cites W4298373620 @default.
• W2297187856 doi "https://doi.org/10.1117/12.2213390" @default.
• W2297187856 hasPublicationYear "2016" @default.
• W2297187856 type Work @default.
• W2297187856 sameAs 2297187856 @default.
• W2297187856 citedByCount "0" @default.
• W2297187856 crossrefType "proceedings-article" @default.
• W2297187856 hasAuthorship W2297187856A5008248756 @default.
• W2297187856 hasAuthorship W2297187856A5050478637 @default.
• W2297187856 hasAuthorship W2297187856A5088830106 @default.
• W2297187856 hasConcept C109156525 @default.
• W2297187856 hasConcept C121332964 @default.
• W2297187856 hasConcept C12554922 @default.
• W2297187856 hasConcept C178790620 @default.
• W2297187856 hasConcept C181817918 @default.
• W2297187856 hasConcept C185592680 @default.
• W2297187856 hasConcept C20251656 @default.
• W2297187856 hasConcept C28859421 @default.
• W2297187856 hasConcept C2993207723 @default.
• W2297187856 hasConcept C540031477 @default.
• W2297187856 hasConcept C55493867 @default.
• W2297187856 hasConcept C55885012 @default.
• W2297187856 hasConcept C57477423 @default.
• W2297187856 hasConcept C57600042 @default.
• W2297187856 hasConcept C62231903 @default.
• W2297187856 hasConcept C62520636 @default.
• W2297187856 hasConcept C86803240 @default.
• W2297187856 hasConcept C91881484 @default.
• W2297187856 hasConcept C95444343 @default.
• W2297187856 hasConceptScore W2297187856C109156525 @default.
• W2297187856 hasConceptScore W2297187856C121332964 @default.
• W2297187856 hasConceptScore W2297187856C12554922 @default.
• W2297187856 hasConceptScore W2297187856C178790620 @default.
• W2297187856 hasConceptScore W2297187856C181817918 @default.
• W2297187856 hasConceptScore W2297187856C185592680 @default.
• W2297187856 hasConceptScore W2297187856C20251656 @default.
• W2297187856 hasConceptScore W2297187856C28859421 @default.
• W2297187856 hasConceptScore W2297187856C2993207723 @default.
• W2297187856 hasConceptScore W2297187856C540031477 @default.
• W2297187856 hasConceptScore W2297187856C55493867 @default.
• W2297187856 hasConceptScore W2297187856C55885012 @default.
• W2297187856 hasConceptScore W2297187856C57477423 @default.
• W2297187856 hasConceptScore W2297187856C57600042 @default.
• W2297187856 hasConceptScore W2297187856C62231903 @default.
• W2297187856 hasConceptScore W2297187856C62520636 @default.
• W2297187856 hasConceptScore W2297187856C86803240 @default.
• W2297187856 hasConceptScore W2297187856C91881484 @default.
• W2297187856 hasConceptScore W2297187856C95444343 @default.
• W2297187856 hasLocation W22971878561 @default.
• W2297187856 hasOpenAccess W2297187856 @default.
• W2297187856 hasPrimaryLocation W22971878561 @default.
• W2297187856 hasRelatedWork W1990512607 @default.
• W2297187856 hasRelatedWork W1994362400 @default.
• W2297187856 hasRelatedWork W1997240553 @default.
• W2297187856 hasRelatedWork W2003648386 @default.

• next