Matches in SemOpenAlex for { <https://semopenalex.org/work/W2297371018> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2297371018 endingPage "R1186" @default.
- W2297371018 startingPage "R1182" @default.
- W2297371018 abstract "Renal interstitial hydrostatic pressure (RIHP) has been implicated in the regulation of sodium excretion. Studies using vasodilators and other maneuvers to increase RIHP have found a significant correlation between RIHP and sodium excretion. Since correlative studies do not prove a cause-and-effect relationship, it is not known whether the rise in sodium excretion in these studies is the result of increases in RIHP or if RIHP is elevated as a result of decreases in sodium and water reabsorption and increases in intratubular pressure. Therefore, the purpose of the present study was to determine whether elevation of intratubular hydrostatic pressures in response to direct inhibition of tubule transport with loop diuretics results in increases in RIHP in dogs and rats. Intrarenal hydrostatic pressures, renal hemodynamics, and sodium and water excretion were examined in dogs during intravenous administration of furosemide (3 mg/kg bolus followed by 0.03 mg.kg-1 x min-1) or bumetanide (60 micrograms/kg bolus followed by 1 microgram.kg-1 x min-1). Furosemide administration increased urinary flow rate (V; 0.10 +/- 0.02 to 4.6 +/- 0.97 ml/min), urinary sodium excretion (UNaV; 16 +/- 5 to 549 +/- 123 mu eq/min), and proximal tubule hydrostatic pressure (PT; 21 +/- 1 to 28 +/- 1 mmHg) but had no effect on RIHP (7.2 +/- 0.6 to 7.4 +/- 0.7 mmHg) or peritubular capillary hydrostatic pressure (14 +/- 1 to 14 +/- 1 mmHg).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2297371018 created "2016-06-24" @default.
- W2297371018 creator A5014000612 @default.
- W2297371018 creator A5014193048 @default.
- W2297371018 creator A5031914841 @default.
- W2297371018 creator A5033919728 @default.
- W2297371018 creator A5071081376 @default.
- W2297371018 date "1992-12-01" @default.
- W2297371018 modified "2023-09-27" @default.
- W2297371018 title "Intrarenal pressures during direct inhibition of sodium transport" @default.
- W2297371018 doi "https://doi.org/10.1152/ajpregu.1992.263.6.r1182" @default.
- W2297371018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1481925" @default.
- W2297371018 hasPublicationYear "1992" @default.
- W2297371018 type Work @default.
- W2297371018 sameAs 2297371018 @default.
- W2297371018 citedByCount "3" @default.
- W2297371018 countsByYear W22973710182015 @default.
- W2297371018 countsByYear W22973710182019 @default.
- W2297371018 crossrefType "journal-article" @default.
- W2297371018 hasAuthorship W2297371018A5014000612 @default.
- W2297371018 hasAuthorship W2297371018A5014193048 @default.
- W2297371018 hasAuthorship W2297371018A5031914841 @default.
- W2297371018 hasAuthorship W2297371018A5033919728 @default.
- W2297371018 hasAuthorship W2297371018A5071081376 @default.
- W2297371018 hasConcept C10146269 @default.
- W2297371018 hasConcept C121332964 @default.
- W2297371018 hasConcept C126322002 @default.
- W2297371018 hasConcept C134018914 @default.
- W2297371018 hasConcept C159641895 @default.
- W2297371018 hasConcept C161457703 @default.
- W2297371018 hasConcept C174459258 @default.
- W2297371018 hasConcept C178790620 @default.
- W2297371018 hasConcept C185592680 @default.
- W2297371018 hasConcept C188053792 @default.
- W2297371018 hasConcept C2777955127 @default.
- W2297371018 hasConcept C2778212192 @default.
- W2297371018 hasConcept C2779547328 @default.
- W2297371018 hasConcept C2910081258 @default.
- W2297371018 hasConcept C43376680 @default.
- W2297371018 hasConcept C537181965 @default.
- W2297371018 hasConcept C55493867 @default.
- W2297371018 hasConcept C56906281 @default.
- W2297371018 hasConcept C57476199 @default.
- W2297371018 hasConcept C71924100 @default.
- W2297371018 hasConcept C97355855 @default.
- W2297371018 hasConceptScore W2297371018C10146269 @default.
- W2297371018 hasConceptScore W2297371018C121332964 @default.
- W2297371018 hasConceptScore W2297371018C126322002 @default.
- W2297371018 hasConceptScore W2297371018C134018914 @default.
- W2297371018 hasConceptScore W2297371018C159641895 @default.
- W2297371018 hasConceptScore W2297371018C161457703 @default.
- W2297371018 hasConceptScore W2297371018C174459258 @default.
- W2297371018 hasConceptScore W2297371018C178790620 @default.
- W2297371018 hasConceptScore W2297371018C185592680 @default.
- W2297371018 hasConceptScore W2297371018C188053792 @default.
- W2297371018 hasConceptScore W2297371018C2777955127 @default.
- W2297371018 hasConceptScore W2297371018C2778212192 @default.
- W2297371018 hasConceptScore W2297371018C2779547328 @default.
- W2297371018 hasConceptScore W2297371018C2910081258 @default.
- W2297371018 hasConceptScore W2297371018C43376680 @default.
- W2297371018 hasConceptScore W2297371018C537181965 @default.
- W2297371018 hasConceptScore W2297371018C55493867 @default.
- W2297371018 hasConceptScore W2297371018C56906281 @default.
- W2297371018 hasConceptScore W2297371018C57476199 @default.
- W2297371018 hasConceptScore W2297371018C71924100 @default.
- W2297371018 hasConceptScore W2297371018C97355855 @default.
- W2297371018 hasIssue "6" @default.
- W2297371018 hasLocation W22973710181 @default.
- W2297371018 hasLocation W22973710182 @default.
- W2297371018 hasOpenAccess W2297371018 @default.
- W2297371018 hasPrimaryLocation W22973710181 @default.
- W2297371018 hasRelatedWork W1971263809 @default.
- W2297371018 hasRelatedWork W1980450509 @default.
- W2297371018 hasRelatedWork W2037919193 @default.
- W2297371018 hasRelatedWork W2040080713 @default.
- W2297371018 hasRelatedWork W2042119917 @default.
- W2297371018 hasRelatedWork W2146826804 @default.
- W2297371018 hasRelatedWork W2259600408 @default.
- W2297371018 hasRelatedWork W2272814798 @default.
- W2297371018 hasRelatedWork W2297371018 @default.
- W2297371018 hasRelatedWork W2462552400 @default.
- W2297371018 hasVolume "263" @default.
- W2297371018 isParatext "false" @default.
- W2297371018 isRetracted "false" @default.
- W2297371018 magId "2297371018" @default.
- W2297371018 workType "article" @default.