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- W2297471452 abstract "Weak mechanical properties and poor protein adsorption capacity of sodium alginate (SA) limit its use in tissue engineering. In this study, glucosamine-grafted nanoplate-like hydroxyapatite (gHAp)–SA nanocomposite scaffolds were fabricated via solution mixture and freeze-drying method. Scanning electron microscopy, X-ray diffraction, Fourier transform infrared, and thermogravimetric analysis were used to characterize the gHAp/SA nanocomposites. The porosity, mechanical properties, and preliminary cell behaviour of the gHAp/SA nanocomposites were examined and compared with neat SA. The gHAp/SA nanocomposites show improved mechanical properties and superior cell viability to neat SA. Furthermore, both the mechanical and biological behaviours of the gHAp/SA nanocomposites are related to the content of gHAp. It has been demonstrated that the highly porous and mechanically robust gHAp/SA nanocomposite scaffolds hold promise in tissue engineering applications." @default.
- W2297471452 created "2016-06-24" @default.
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- W2297471452 date "2016-01-08" @default.
- W2297471452 modified "2023-09-25" @default.
- W2297471452 title "Porous nanoplate-like hydroxyapatite–sodium alginate nanocomposite scaffolds for potential bone tissue engineering" @default.
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- W2297471452 doi "https://doi.org/10.1080/10667857.2015.1125045" @default.
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