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• W2297500895 abstract "<p class=western align=justify><span style=font-family: Calibri, serif;><span><span style=font-family: Arial, serif;><span><span lang=en-US>The immune system plays an important role in the pathogenesis of periodontal diseases. The host may modulate periodontal inflammatory reactions and it determines variances in the individual susceptibility and in the periodontal disease progression speed. Osteoporosis and alcoholism are described as risk indicators of periodontal disease among the systemic acquired factors.</span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US><strong> Objective: </strong></span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US>The current study aims to analyze chronic alcohol consumption influence on induced periodontitis in rats presenting estrogen deficiency. </span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US><strong>Material and Methods: </strong></span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US>Sixty rats approximately 90 days old were used in the experiment; they were divided into two groups: correlated surgery (OVZ) or surgical ovariectomy simulation (SHAM). Each group was divided into three subgroups: (C) control diet, (A) ethanol containing 20% liquid diet and (I) par-fed control diet. Thirty days after castration the diet and the experimental periodontitis induction were kept for 56 days. Interproximal regions between the first and the second lower left molar and the respective contralateral site without periodontal disease induction were assessed for inflammatory features. </span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US><strong>Results: </strong></span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US>Hormone deficiency resulted in important inflammatory changes concerning the meaning of SHAM-C and OVZ-C. The ethanol diet has resulted in inflammatory changes to both groups SHAM-A and OVZ-A in the absence of periodontitis, with also greater severity when combined with ovariectomy. </span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US><strong>Conclusion:</strong></span></span></span><span style=font-family: Arial, serif;><span><span lang=en-US> It was concluded that the association between estrogen deficiency and 20% ethanol was just relevant for sites without periodontitis disease induction, since it induces stronger severity in the inflammatory process in the presence of the inflammatory cells scattered in the conjunctive tissue and of the disorientation of periodontal ligament fibers. </span></span></span></span></span></p><p class=western align=justify><span style=font-family: Calibri, serif;><span><span style=font-family: Arial, serif;><span><span lang=en-US><strong>Keywords</strong></span></span></span></span></span></p><p class=western align=justify><span style=font-family: Arial, serif;>Alcoholism; Osteoporosis; Ovariectomy; Periodontal disease. </span></p>" @default.
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• W2297500895 date "2016-03-14" @default.
• W2297500895 modified "2023-09-30" @default.
• W2297500895 title "Periodontal inflammation induced by chronic ethanol consumption in ovariectomized rats" @default.
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• W2297500895 doi "https://doi.org/10.14295/bds.2016.v19i1.1197" @default.
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