Matches in SemOpenAlex for { <https://semopenalex.org/work/W2297508409> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2297508409 abstract "Carbon ion therapy is a type of radiotherapy that can deliver high-dose radiation to a tumor while minimizing the dose delivered to organs at risk. Moreover, carbon ions are classified as high linear energy transfer radiation and are expected to be effective for even photon-resistant tumors. A 73-year-old man with glottic squamous cell carcinoma, T3N0M0, refused laryngectomy and received carbon ion therapy of 70 Gy (relative biological effectiveness) in 35 fractions. Three months after the therapy, the patient had an upper airway inflammation, and then laryngeal edema and pain occurred. Five months after the therapy, the airway stenosis was severe and computed tomography showed lack of the left arytenoid cartilage and exacerbation of laryngeal necrosis. Despite the treatment, 5 and a half months after the therapy, the laryngeal edema and necrosis had become even worse and the surrounding mucosa was edematous and pale. Six months after the therapy, pharyngolaryngoesophagectomy and reconstruction with free jejunal autograft were performed. The surgical specimen pathologically showed massive necrosis and no residual tumor. Three years after the carbon ion therapy, he is alive without recurrence. The first reported laryngeal squamous cell carcinoma case treated with carbon ion therapy resulted in an unexpected radiation laryngeal necrosis. Tissue damage caused by carbon ion therapy may be difficult to repair even for radioresistant cartilage; therefore, hollow organs reinforced by cartilage, such as the larynx, may be vulnerable to carbon ion therapy. Caution should be exercised when treating tumors in or adjacent to such organs with carbon ion therapy." @default.
- W2297508409 created "2016-06-24" @default.
- W2297508409 creator A5000964587 @default.
- W2297508409 creator A5003214268 @default.
- W2297508409 creator A5007089706 @default.
- W2297508409 creator A5007615439 @default.
- W2297508409 creator A5018944066 @default.
- W2297508409 creator A5022734887 @default.
- W2297508409 creator A5041084087 @default.
- W2297508409 creator A5045012751 @default.
- W2297508409 creator A5050491832 @default.
- W2297508409 creator A5080516835 @default.
- W2297508409 creator A5080942624 @default.
- W2297508409 creator A5085120649 @default.
- W2297508409 date "2015-09-09" @default.
- W2297508409 modified "2023-10-01" @default.
- W2297508409 title "Unexpected radiation laryngeal necrosis after carbon ion therapy using conventional dose fractionation for laryngeal cancer" @default.
- W2297508409 cites W1225762945 @default.
- W2297508409 cites W1975210359 @default.
- W2297508409 cites W1981278871 @default.
- W2297508409 cites W1995631349 @default.
- W2297508409 cites W2015755717 @default.
- W2297508409 cites W2050196300 @default.
- W2297508409 cites W2056329585 @default.
- W2297508409 cites W2058784227 @default.
- W2297508409 cites W2062331619 @default.
- W2297508409 cites W2065840535 @default.
- W2297508409 cites W2077109339 @default.
- W2297508409 cites W2084850974 @default.
- W2297508409 cites W2085138873 @default.
- W2297508409 cites W2085202845 @default.
- W2297508409 cites W2085928045 @default.
- W2297508409 cites W2087643587 @default.
- W2297508409 cites W2089969159 @default.
- W2297508409 cites W2090400923 @default.
- W2297508409 cites W2114035136 @default.
- W2297508409 cites W2121429754 @default.
- W2297508409 cites W2129563044 @default.
- W2297508409 cites W2136744417 @default.
- W2297508409 cites W2144084582 @default.
- W2297508409 cites W2144739220 @default.
- W2297508409 cites W2145005596 @default.
- W2297508409 cites W2155907962 @default.
- W2297508409 cites W2158686595 @default.
- W2297508409 cites W2159192512 @default.
- W2297508409 cites W2160805185 @default.
- W2297508409 cites W2166676532 @default.
- W2297508409 cites W2182428147 @default.
- W2297508409 doi "https://doi.org/10.1093/jjco/hyv121" @default.
- W2297508409 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26355161" @default.
- W2297508409 hasPublicationYear "2015" @default.
- W2297508409 type Work @default.
- W2297508409 sameAs 2297508409 @default.
- W2297508409 citedByCount "5" @default.
- W2297508409 countsByYear W22975084092016 @default.
- W2297508409 countsByYear W22975084092018 @default.
- W2297508409 countsByYear W22975084092019 @default.
- W2297508409 countsByYear W22975084092023 @default.
- W2297508409 crossrefType "journal-article" @default.
- W2297508409 hasAuthorship W2297508409A5000964587 @default.
- W2297508409 hasAuthorship W2297508409A5003214268 @default.
- W2297508409 hasAuthorship W2297508409A5007089706 @default.
- W2297508409 hasAuthorship W2297508409A5007615439 @default.
- W2297508409 hasAuthorship W2297508409A5018944066 @default.
- W2297508409 hasAuthorship W2297508409A5022734887 @default.
- W2297508409 hasAuthorship W2297508409A5041084087 @default.
- W2297508409 hasAuthorship W2297508409A5045012751 @default.
- W2297508409 hasAuthorship W2297508409A5050491832 @default.
- W2297508409 hasAuthorship W2297508409A5080516835 @default.
- W2297508409 hasAuthorship W2297508409A5080942624 @default.
- W2297508409 hasAuthorship W2297508409A5085120649 @default.
- W2297508409 hasBestOaLocation W22975084091 @default.
- W2297508409 hasConcept C141071460 @default.
- W2297508409 hasConcept C142724271 @default.
- W2297508409 hasConcept C2780474809 @default.
- W2297508409 hasConcept C2780886150 @default.
- W2297508409 hasConcept C2910317908 @default.
- W2297508409 hasConcept C503630168 @default.
- W2297508409 hasConcept C509974204 @default.
- W2297508409 hasConcept C71924100 @default.
- W2297508409 hasConceptScore W2297508409C141071460 @default.
- W2297508409 hasConceptScore W2297508409C142724271 @default.
- W2297508409 hasConceptScore W2297508409C2780474809 @default.
- W2297508409 hasConceptScore W2297508409C2780886150 @default.
- W2297508409 hasConceptScore W2297508409C2910317908 @default.
- W2297508409 hasConceptScore W2297508409C503630168 @default.
- W2297508409 hasConceptScore W2297508409C509974204 @default.
- W2297508409 hasConceptScore W2297508409C71924100 @default.
- W2297508409 hasLocation W22975084091 @default.
- W2297508409 hasLocation W22975084092 @default.
- W2297508409 hasOpenAccess W2297508409 @default.
- W2297508409 hasPrimaryLocation W22975084091 @default.
- W2297508409 isParatext "false" @default.
- W2297508409 isRetracted "false" @default.
- W2297508409 magId "2297508409" @default.
- W2297508409 workType "article" @default.