Matches in SemOpenAlex for { <https://semopenalex.org/work/W2297676974> ?p ?o ?g. }
- W2297676974 abstract "A common problem in Phase II clinical trials is the comparison of dose response curves corresponding to different treatment groups. If the effect of the dose level is described by parametric regression models and the treatments differ in the administration frequency (but not in the sort of drug) a reasonable assumption is that the regression models for the different treatments share common parameters. This paper develops optimal design theory for the comparison of different regression models with common parameters. We derive upper bounds on the number of support points of admissible designs, and explicit expressions for $D$-optimal designs are derived for frequently used dose response models with a common location parameter. If the location and scale parameter in the different models coincide, minimally supported designs are determined and sufficient conditions for their optimality in the class of all designs derived. The results are illustrated in a dose-finding study comparing monthly and weekly administration." @default.
- W2297676974 created "2016-06-24" @default.
- W2297676974 creator A5037794163 @default.
- W2297676974 creator A5052180556 @default.
- W2297676974 creator A5056814618 @default.
- W2297676974 creator A5060734352 @default.
- W2297676974 creator A5013007833 @default.
- W2297676974 date "2016-03-14" @default.
- W2297676974 modified "2023-09-27" @default.
- W2297676974 title "Optimal designs for dose response curves with common parameters" @default.
- W2297676974 cites W1515666340 @default.
- W2297676974 cites W1973002971 @default.
- W2297676974 cites W1974728574 @default.
- W2297676974 cites W1990344145 @default.
- W2297676974 cites W2006121606 @default.
- W2297676974 cites W2014018052 @default.
- W2297676974 cites W2017351261 @default.
- W2297676974 cites W2037224035 @default.
- W2297676974 cites W2039220745 @default.
- W2297676974 cites W2048144055 @default.
- W2297676974 cites W2055163450 @default.
- W2297676974 cites W2071658642 @default.
- W2297676974 cites W2082382318 @default.
- W2297676974 cites W2099447036 @default.
- W2297676974 cites W2114800482 @default.
- W2297676974 cites W2121449016 @default.
- W2297676974 cites W2124562077 @default.
- W2297676974 cites W2156195892 @default.
- W2297676974 cites W2797925981 @default.
- W2297676974 cites W3100447146 @default.
- W2297676974 cites W3106253201 @default.
- W2297676974 hasPublicationYear "2016" @default.
- W2297676974 type Work @default.
- W2297676974 sameAs 2297676974 @default.
- W2297676974 citedByCount "0" @default.
- W2297676974 crossrefType "posted-content" @default.
- W2297676974 hasAuthorship W2297676974A5013007833 @default.
- W2297676974 hasAuthorship W2297676974A5037794163 @default.
- W2297676974 hasAuthorship W2297676974A5052180556 @default.
- W2297676974 hasAuthorship W2297676974A5056814618 @default.
- W2297676974 hasAuthorship W2297676974A5060734352 @default.
- W2297676974 hasConcept C105795698 @default.
- W2297676974 hasConcept C117251300 @default.
- W2297676974 hasConcept C121332964 @default.
- W2297676974 hasConcept C126255220 @default.
- W2297676974 hasConcept C152877465 @default.
- W2297676974 hasConcept C154945302 @default.
- W2297676974 hasConcept C186394612 @default.
- W2297676974 hasConcept C24574437 @default.
- W2297676974 hasConcept C2777212361 @default.
- W2297676974 hasConcept C2778755073 @default.
- W2297676974 hasConcept C28826006 @default.
- W2297676974 hasConcept C33923547 @default.
- W2297676974 hasConcept C41008148 @default.
- W2297676974 hasConcept C62520636 @default.
- W2297676974 hasConcept C83546350 @default.
- W2297676974 hasConcept C88548561 @default.
- W2297676974 hasConcept C94375191 @default.
- W2297676974 hasConceptScore W2297676974C105795698 @default.
- W2297676974 hasConceptScore W2297676974C117251300 @default.
- W2297676974 hasConceptScore W2297676974C121332964 @default.
- W2297676974 hasConceptScore W2297676974C126255220 @default.
- W2297676974 hasConceptScore W2297676974C152877465 @default.
- W2297676974 hasConceptScore W2297676974C154945302 @default.
- W2297676974 hasConceptScore W2297676974C186394612 @default.
- W2297676974 hasConceptScore W2297676974C24574437 @default.
- W2297676974 hasConceptScore W2297676974C2777212361 @default.
- W2297676974 hasConceptScore W2297676974C2778755073 @default.
- W2297676974 hasConceptScore W2297676974C28826006 @default.
- W2297676974 hasConceptScore W2297676974C33923547 @default.
- W2297676974 hasConceptScore W2297676974C41008148 @default.
- W2297676974 hasConceptScore W2297676974C62520636 @default.
- W2297676974 hasConceptScore W2297676974C83546350 @default.
- W2297676974 hasConceptScore W2297676974C88548561 @default.
- W2297676974 hasConceptScore W2297676974C94375191 @default.
- W2297676974 hasLocation W22976769741 @default.
- W2297676974 hasOpenAccess W2297676974 @default.
- W2297676974 hasPrimaryLocation W22976769741 @default.
- W2297676974 hasRelatedWork W1984216444 @default.
- W2297676974 hasRelatedWork W1997557924 @default.
- W2297676974 hasRelatedWork W2007610448 @default.
- W2297676974 hasRelatedWork W2026936525 @default.
- W2297676974 hasRelatedWork W2029953425 @default.
- W2297676974 hasRelatedWork W2040801888 @default.
- W2297676974 hasRelatedWork W2044349746 @default.
- W2297676974 hasRelatedWork W2067483022 @default.
- W2297676974 hasRelatedWork W2093822077 @default.
- W2297676974 hasRelatedWork W2096980165 @default.
- W2297676974 hasRelatedWork W2149201411 @default.
- W2297676974 hasRelatedWork W2185101500 @default.
- W2297676974 hasRelatedWork W2336704427 @default.
- W2297676974 hasRelatedWork W2605132092 @default.
- W2297676974 hasRelatedWork W3106324198 @default.
- W2297676974 hasRelatedWork W3123596296 @default.
- W2297676974 hasRelatedWork W3125001813 @default.
- W2297676974 hasRelatedWork W3746686 @default.
- W2297676974 hasRelatedWork W581014842 @default.
- W2297676974 hasRelatedWork W61004142 @default.
- W2297676974 isParatext "false" @default.
- W2297676974 isRetracted "false" @default.