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- W2297992246 abstract "Fifty five genes coding for polyproteins in foot and mouth disease virus (FMDV) serotype A and serotype O had been analyzed in term of variance analysis,in which 27 genes coding for polyproteins belonged to serotype A,the rest coding for polyproteins of serotype O. It had been observed that codon in different codons (including GCC,GCG,AGA,CGG,GGC,GGU,CAC,CAU,AUA,AUU,CUG,CCC,AGC,UCU,ACA,ACC,ACG,ACU) was significantly different. However,by analysis of the amino acid usage,it was found that only Ala,Arg,Leu,Phe,Ser were significant at the amino acid usage. These results indicate that the codon provides more informations than the amino acid usage. In addition,through analysis of the general pattern of codon between serotype A and serotype O,the comparison of the two serotypes with large amount of codons shows that the codon of two serotypes may be correspondent to tRNA abundance. Also these results put concept of relative synonymous codon usage (RSCU) into a novel perspective to mutation of FMDV. The internal connectivity of synonymous codons indicates that all synonymous codons may take part in some selection mechanisms." @default.
- W2297992246 created "2016-06-24" @default.
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- W2297992246 date "2010-01-01" @default.
- W2297992246 modified "2023-09-26" @default.
- W2297992246 title "Codon usage of the polyprotein coding sequence in foot and mouth disease virus serotype A and serotype O." @default.
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