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- W2298441444 abstract "Merkel cell carcinoma (MCC) is a rare primary cutaneous neuroendocrine carcinoma first described by Toker in 1972. These cells are thought to originate from the neural crest and act as mechanoreceptors. They typically occur in the head and neck area of the elderly patients and appear as a firm cutaneous nodule or indurated plaque which may be blue or pink in color. The tumor often follows an aggressive course with frequent local recurrences and regional metastasis as well as distant metastasis. The biologic behavior has been compared with a variant of melanoma. Wide surgical resection of the primary lesion (with a margin of 2.5-3 cm) is the key of treatement and coupled with therapeutic lymph node dissection and/or radiation when present with local or regional metastasis. For further understanding of the nature history of MCC and the effect of various treatment options, we like to describe each case individually as were stressed by others. We, therefore present our four patients of MCC proven by immunohistochemistry and literature are reviewed." @default.
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- W2298441444 date "1997-03-01" @default.
- W2298441444 modified "2023-09-24" @default.
- W2298441444 title "Merkel Cell Carcinoma: Four Cases Report & Literature Review" @default.
- W2298441444 doi "https://doi.org/10.7096/jprsa.199703.0048" @default.
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