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- W22991503 endingPage "349" @default.
- W22991503 startingPage "299" @default.
- W22991503 abstract "Multilocus Enzyme Electrophoresis (MEE) and Multilocus Sequence Typing (MLST) is a powerful new approach for the characterization of microorganisms, because it provides unambiguous molecular typing data that are electronically portable between laboratories, and that can be used in studies of global epidemiology. The technique is based on the analysis of electrophoretic variation in a set of chromosomally encoded cytoplasmic enzymes. For several species of bacteria, the genetic relationships obtained by MEE have been shown to be strongly correlated with those obtained from DNA-DNA hybridisation analysis. MLST schemes for Staph. aureus, Strep. pyogenes, H. influenzae, Yersinia spp., and other major pathogens are under development. MLST is a simple technique that requires only the ability to amplify specific DNA fragments by PCR and to sequence those fragments. While the method is still quite expensive, further technological developments in automated sequencing should soon render MLST accessible to all major public health laboratories, including those in the developing world. In line with the impact of MEE, MLST will further improve the understanding of the population and evolutionary biology of microbial pathogens, as well as other microorganisms. For the more stable microbial pathogens, sequence analysis of one or a few hypervariable loci, in addition to the MLST scheme based on housekeeping genes, will provide a versatile tool for studies of both global and local epidemiology." @default.
- W22991503 created "2016-06-24" @default.
- W22991503 creator A5009940787 @default.
- W22991503 date "2001-01-01" @default.
- W22991503 modified "2023-09-25" @default.
- W22991503 title "From Multilocus Enzyme Electrophoresis to Multilocus Sequence Typing" @default.
- W22991503 cites W1480350832 @default.
- W22991503 cites W1483772280 @default.
- W22991503 cites W1489673870 @default.
- W22991503 cites W1506621356 @default.
- W22991503 cites W1509344099 @default.
- W22991503 cites W1516183432 @default.
- W22991503 cites W1527004061 @default.
- W22991503 cites W1530076799 @default.
- W22991503 cites W1546278883 @default.
- W22991503 cites W1559568857 @default.
- W22991503 cites W1559805484 @default.
- W22991503 cites W1566021998 @default.
- W22991503 cites W1577024859 @default.
- W22991503 cites W1582991270 @default.
- W22991503 cites W1590884759 @default.
- W22991503 cites W1595425497 @default.
- W22991503 cites W1612381723 @default.
- W22991503 cites W1630870787 @default.
- W22991503 cites W1648810964 @default.
- W22991503 cites W1649296781 @default.
- W22991503 cites W1664080268 @default.
- W22991503 cites W1687407020 @default.
- W22991503 cites W1711559289 @default.
- W22991503 cites W1742447035 @default.
- W22991503 cites W1749803995 @default.
- W22991503 cites W1750798266 @default.
- W22991503 cites W1772518584 @default.
- W22991503 cites W1772675371 @default.
- W22991503 cites W1813719879 @default.
- W22991503 cites W1815709022 @default.
- W22991503 cites W1825878074 @default.
- W22991503 cites W1831779980 @default.
- W22991503 cites W1838481787 @default.
- W22991503 cites W1844831948 @default.
- W22991503 cites W1859496595 @default.
- W22991503 cites W1869773175 @default.
- W22991503 cites W1871784133 @default.
- W22991503 cites W1881718427 @default.
- W22991503 cites W1884605757 @default.
- W22991503 cites W1889832856 @default.
- W22991503 cites W1896410724 @default.
- W22991503 cites W1899016518 @default.
- W22991503 cites W1902575090 @default.
- W22991503 cites W1905556451 @default.
- W22991503 cites W1907149689 @default.
- W22991503 cites W1924473659 @default.
- W22991503 cites W1930167094 @default.
- W22991503 cites W1935781302 @default.
- W22991503 cites W1940132199 @default.
- W22991503 cites W1943568844 @default.
- W22991503 cites W1945134562 @default.
- W22991503 cites W1968496641 @default.
- W22991503 cites W1968849192 @default.
- W22991503 cites W1970273856 @default.
- W22991503 cites W1972409953 @default.
- W22991503 cites W1972638383 @default.
- W22991503 cites W1973079579 @default.
- W22991503 cites W1975408746 @default.
- W22991503 cites W1975660775 @default.
- W22991503 cites W1975684057 @default.
- W22991503 cites W1977414953 @default.
- W22991503 cites W1985757191 @default.
- W22991503 cites W1985891064 @default.
- W22991503 cites W1990350059 @default.
- W22991503 cites W1991369558 @default.
- W22991503 cites W1992909494 @default.
- W22991503 cites W1997053840 @default.
- W22991503 cites W1997230014 @default.
- W22991503 cites W1998362120 @default.
- W22991503 cites W2002537247 @default.
- W22991503 cites W2004260915 @default.
- W22991503 cites W2014408406 @default.
- W22991503 cites W2015011454 @default.
- W22991503 cites W2015071529 @default.
- W22991503 cites W2015185941 @default.
- W22991503 cites W2015271177 @default.
- W22991503 cites W2016361506 @default.
- W22991503 cites W2020835792 @default.
- W22991503 cites W2022821820 @default.
- W22991503 cites W2022896111 @default.
- W22991503 cites W2026413648 @default.
- W22991503 cites W2027744365 @default.
- W22991503 cites W2028383361 @default.
- W22991503 cites W2028742894 @default.
- W22991503 cites W2028998553 @default.
- W22991503 cites W2029771613 @default.
- W22991503 cites W2032054573 @default.
- W22991503 cites W2034314971 @default.
- W22991503 cites W2035325939 @default.
- W22991503 cites W2035892027 @default.
- W22991503 cites W2035913554 @default.
- W22991503 cites W2039412760 @default.