Matches in SemOpenAlex for { <https://semopenalex.org/work/W2299532471> ?p ?o ?g. }
- W2299532471 endingPage "4020" @default.
- W2299532471 startingPage "4014" @default.
- W2299532471 abstract "Silver is a very common heavy metal, and its detection is of significant analytical importance. DNAzymes are DNA-based catalysts; they typically recruit divalent and trivalent metal ions for catalysis. Herein, we report a silver-specific RNA-cleaving DNAzyme named Ag10c obtained after six rounds of in vitro selection. Ag10c displays a catalytic rate of 0.41 min(-1) with 10 μM Ag(+) at pH 7.5 with 200 mM NaNO3, while its activity is completely inhibited with the same concentration of NaCl. Ag10c is highly specific for Ag(+) among all the tested metals. A catalytic beacon biosensor is designed by labeling a fluorophore and a quencher on the DNAzyme. Fluorescence enhancement is observed in the presence of Ag(+) with a detection limit of 24.9 nM Ag(+). The sensor shows a similar analytical performance in Lake Huron water. This is the first monovalent transition metal dependent RNA-cleaving DNAzyme. Apart from its biosensor application, this study strengthens the idea of exploring beyond the traditional understanding of multivalent ion dependent DNAzyme catalysis." @default.
- W2299532471 created "2016-06-24" @default.
- W2299532471 creator A5062110039 @default.
- W2299532471 creator A5087037080 @default.
- W2299532471 date "2016-03-24" @default.
- W2299532471 modified "2023-10-03" @default.
- W2299532471 title "A Silver DNAzyme" @default.
- W2299532471 cites W1964261732 @default.
- W2299532471 cites W1966162633 @default.
- W2299532471 cites W1976504036 @default.
- W2299532471 cites W1979073863 @default.
- W2299532471 cites W1984763177 @default.
- W2299532471 cites W1986764455 @default.
- W2299532471 cites W1987565198 @default.
- W2299532471 cites W1990534283 @default.
- W2299532471 cites W1999091059 @default.
- W2299532471 cites W2000914047 @default.
- W2299532471 cites W2002661845 @default.
- W2299532471 cites W2002854512 @default.
- W2299532471 cites W2004252984 @default.
- W2299532471 cites W2009932039 @default.
- W2299532471 cites W2017031026 @default.
- W2299532471 cites W2024549410 @default.
- W2299532471 cites W2024550183 @default.
- W2299532471 cites W2035562017 @default.
- W2299532471 cites W2036821913 @default.
- W2299532471 cites W2041659526 @default.
- W2299532471 cites W2044006090 @default.
- W2299532471 cites W2047845427 @default.
- W2299532471 cites W2062275444 @default.
- W2299532471 cites W2069688986 @default.
- W2299532471 cites W2071308556 @default.
- W2299532471 cites W2071597330 @default.
- W2299532471 cites W2073775872 @default.
- W2299532471 cites W2083733102 @default.
- W2299532471 cites W2086757937 @default.
- W2299532471 cites W2093002330 @default.
- W2299532471 cites W2095469093 @default.
- W2299532471 cites W2099958243 @default.
- W2299532471 cites W2120434145 @default.
- W2299532471 cites W2120749428 @default.
- W2299532471 cites W2123847150 @default.
- W2299532471 cites W2129197362 @default.
- W2299532471 cites W2137695857 @default.
- W2299532471 cites W2138613437 @default.
- W2299532471 cites W2138721711 @default.
- W2299532471 cites W2141157874 @default.
- W2299532471 cites W2142408722 @default.
- W2299532471 cites W2172169019 @default.
- W2299532471 cites W2172464129 @default.
- W2299532471 cites W2180386600 @default.
- W2299532471 cites W2195620554 @default.
- W2299532471 cites W2329360889 @default.
- W2299532471 cites W2335093845 @default.
- W2299532471 cites W2338479504 @default.
- W2299532471 cites W2058475816 @default.
- W2299532471 doi "https://doi.org/10.1021/acs.analchem.6b00327" @default.
- W2299532471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26977895" @default.
- W2299532471 hasPublicationYear "2016" @default.
- W2299532471 type Work @default.
- W2299532471 sameAs 2299532471 @default.
- W2299532471 citedByCount "158" @default.
- W2299532471 countsByYear W22995324712016 @default.
- W2299532471 countsByYear W22995324712017 @default.
- W2299532471 countsByYear W22995324712018 @default.
- W2299532471 countsByYear W22995324712019 @default.
- W2299532471 countsByYear W22995324712020 @default.
- W2299532471 countsByYear W22995324712021 @default.
- W2299532471 countsByYear W22995324712022 @default.
- W2299532471 countsByYear W22995324712023 @default.
- W2299532471 crossrefType "journal-article" @default.
- W2299532471 hasAuthorship W2299532471A5062110039 @default.
- W2299532471 hasAuthorship W2299532471A5087037080 @default.
- W2299532471 hasBestOaLocation W22995324712 @default.
- W2299532471 hasConcept C104317684 @default.
- W2299532471 hasConcept C119128265 @default.
- W2299532471 hasConcept C121332964 @default.
- W2299532471 hasConcept C160756335 @default.
- W2299532471 hasConcept C161790260 @default.
- W2299532471 hasConcept C171250308 @default.
- W2299532471 hasConcept C178790620 @default.
- W2299532471 hasConcept C179104552 @default.
- W2299532471 hasConcept C185592680 @default.
- W2299532471 hasConcept C192562407 @default.
- W2299532471 hasConcept C199164860 @default.
- W2299532471 hasConcept C21951064 @default.
- W2299532471 hasConcept C2778617687 @default.
- W2299532471 hasConcept C43617362 @default.
- W2299532471 hasConcept C544153396 @default.
- W2299532471 hasConcept C55493867 @default.
- W2299532471 hasConcept C62520636 @default.
- W2299532471 hasConcept C67705224 @default.
- W2299532471 hasConcept C74884574 @default.
- W2299532471 hasConcept C84211826 @default.
- W2299532471 hasConcept C91881484 @default.
- W2299532471 hasConceptScore W2299532471C104317684 @default.
- W2299532471 hasConceptScore W2299532471C119128265 @default.
- W2299532471 hasConceptScore W2299532471C121332964 @default.