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- W2299688914 abstract "To assess the safety of Echinacea herb on the reproduction and development of SD rats,a teratogenicity test of Echinacea herb was carried out in SD rats.The SD rats were divided into negative control,positive control and three experiment groups,and Echinacea herb powder was administered by gavage during gestation from day 7 to day 16 at doses of 1g/kg,0.5g/kg or 0.05g/kg to the SD rats in the 3 experiment groups,respectively.Body weight gain of the pregnant rats,and body weight,body length and tail length of live fetus and some other parameters of embryonic development were measured.In result,the weight gain of the pregnant rats,and the body weight,body length and tail length of the fetus were significantly higher than that in the positive control group(P0.01),but the absorbing fetus counts,dead fetus counts and teratosis rate of fetus were significantly lower than that in the positive control group(P0.01 or P0.05).The all above-mentioned indexes in the 3 experiment groups were not significantly different from that in the negative control group(P0.05).In conclusion,The Echinacea herb powder had no maternal,or embryo toxicity and no teratogenic effect to SD rats." @default.
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- W2299688914 date "2010-01-01" @default.
- W2299688914 modified "2023-09-27" @default.
- W2299688914 title "Study on the teratogenicity of Echinacea herb powder in SD rats." @default.
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