FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2299937029> ?p ?o ?g. }

• W2299937029 endingPage "305" @default.
• W2299937029 startingPage "287" @default.
• W2299937029 abstract "Aims: Some allogeneic cell therapies requiring a high dose of cells for large indication groups demand a change in cell expansion technology, from planar units to microcarriers in single-use bioreactors for the market phase. The aim was to model the optimal timing for making this change. Materials & methods: A development lifecycle cash flow framework was created to examine the implications of process changes to microcarrier cultures at different stages of a cell therapy's lifecycle. Results: The analysis performed under assumptions used in the framework predicted that making this switch earlier in development is optimal from a total expected out-of-pocket cost perspective. From a risk-adjusted net present value view, switching at Phase I is economically competitive but a post-approval switch can offer the highest risk-adjusted net present value as the cost of switching is offset by initial market penetration with planar technologies. Conclusion: The framework can facilitate early decision-making during process development." @default.
• W2299937029 created "2016-06-24" @default.
• W2299937029 creator A5013776830 @default.
• W2299937029 creator A5028677147 @default.
• W2299937029 creator A5050572000 @default.
• W2299937029 creator A5055218682 @default.
• W2299937029 creator A5070768786 @default.
• W2299937029 creator A5074068555 @default.
• W2299937029 creator A5083753496 @default.
• W2299937029 date "2016-04-01" @default.
• W2299937029 modified "2023-10-03" @default.
• W2299937029 title "Process change evaluation framework for allogeneic cell therapies: impact on drug development and commercialization" @default.
• W2299937029 cites W1846004257 @default.
• W2299937029 cites W1894559552 @default.
• W2299937029 cites W1974818916 @default.
• W2299937029 cites W1994600065 @default.
• W2299937029 cites W2003964325 @default.
• W2299937029 cites W2010618607 @default.
• W2299937029 cites W2021972578 @default.
• W2299937029 cites W2028401005 @default.
• W2299937029 cites W2043278711 @default.
• W2299937029 cites W2080896315 @default.
• W2299937029 cites W2085575701 @default.
• W2299937029 cites W2090712456 @default.
• W2299937029 cites W2097463815 @default.
• W2299937029 cites W2132875813 @default.
• W2299937029 cites W2162740029 @default.
• W2299937029 cites W2166550586 @default.
• W2299937029 cites W4301816015 @default.
• W2299937029 doi "https://doi.org/10.2217/rme-2015-0034" @default.
• W2299937029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26979513" @default.
• W2299937029 hasPublicationYear "2016" @default.
• W2299937029 type Work @default.
• W2299937029 sameAs 2299937029 @default.
• W2299937029 citedByCount "18" @default.
• W2299937029 countsByYear W22999370292016 @default.
• W2299937029 countsByYear W22999370292017 @default.
• W2299937029 countsByYear W22999370292018 @default.
• W2299937029 countsByYear W22999370292019 @default.
• W2299937029 countsByYear W22999370292020 @default.
• W2299937029 countsByYear W22999370292021 @default.
• W2299937029 countsByYear W22999370292022 @default.
• W2299937029 countsByYear W22999370292023 @default.
• W2299937029 crossrefType "journal-article" @default.
• W2299937029 hasAuthorship W2299937029A5013776830 @default.
• W2299937029 hasAuthorship W2299937029A5028677147 @default.
• W2299937029 hasAuthorship W2299937029A5050572000 @default.
• W2299937029 hasAuthorship W2299937029A5055218682 @default.
• W2299937029 hasAuthorship W2299937029A5070768786 @default.
• W2299937029 hasAuthorship W2299937029A5074068555 @default.
• W2299937029 hasAuthorship W2299937029A5083753496 @default.
• W2299937029 hasBestOaLocation W22999370292 @default.
• W2299937029 hasConcept C111919701 @default.
• W2299937029 hasConcept C112930515 @default.
• W2299937029 hasConcept C121955636 @default.
• W2299937029 hasConcept C144133560 @default.
• W2299937029 hasConcept C1491633281 @default.
• W2299937029 hasConcept C162324750 @default.
• W2299937029 hasConcept C162853370 @default.
• W2299937029 hasConcept C163428354 @default.
• W2299937029 hasConcept C176999471 @default.
• W2299937029 hasConcept C195094911 @default.
• W2299937029 hasConcept C21547014 @default.
• W2299937029 hasConcept C2777648813 @default.
• W2299937029 hasConcept C2780625559 @default.
• W2299937029 hasConcept C2988729646 @default.
• W2299937029 hasConcept C41008148 @default.
• W2299937029 hasConcept C54355233 @default.
• W2299937029 hasConcept C86803240 @default.
• W2299937029 hasConcept C98045186 @default.
• W2299937029 hasConceptScore W2299937029C111919701 @default.
• W2299937029 hasConceptScore W2299937029C112930515 @default.
• W2299937029 hasConceptScore W2299937029C121955636 @default.
• W2299937029 hasConceptScore W2299937029C144133560 @default.
• W2299937029 hasConceptScore W2299937029C1491633281 @default.
• W2299937029 hasConceptScore W2299937029C162324750 @default.
• W2299937029 hasConceptScore W2299937029C162853370 @default.
• W2299937029 hasConceptScore W2299937029C163428354 @default.
• W2299937029 hasConceptScore W2299937029C176999471 @default.
• W2299937029 hasConceptScore W2299937029C195094911 @default.
• W2299937029 hasConceptScore W2299937029C21547014 @default.
• W2299937029 hasConceptScore W2299937029C2777648813 @default.
• W2299937029 hasConceptScore W2299937029C2780625559 @default.
• W2299937029 hasConceptScore W2299937029C2988729646 @default.
• W2299937029 hasConceptScore W2299937029C41008148 @default.
• W2299937029 hasConceptScore W2299937029C54355233 @default.
• W2299937029 hasConceptScore W2299937029C86803240 @default.
• W2299937029 hasConceptScore W2299937029C98045186 @default.
• W2299937029 hasIssue "3" @default.
• W2299937029 hasLocation W22999370291 @default.
• W2299937029 hasLocation W22999370292 @default.
• W2299937029 hasLocation W22999370293 @default.
• W2299937029 hasLocation W22999370294 @default.
• W2299937029 hasOpenAccess W2299937029 @default.
• W2299937029 hasPrimaryLocation W22999370291 @default.
• W2299937029 hasRelatedWork W1554497824 @default.
• W2299937029 hasRelatedWork W1979107141 @default.
• W2299937029 hasRelatedWork W2299937029 @default.

• next