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- W2299980382 endingPage "265" @default.
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- W2299980382 abstract "Primary sclerosing cholangitis (PSC) remains a rare but significant disease, which affects mainly young males in association with inflammatory bowel disease. There have been few advances in the understanding of the pathogenesis of the condition and no therapeutics with proven mortality benefit aside from liver transplantation. There remain areas of controversy in the management of PSC which include the differentiation from other cholangiopathies, in particular immunoglobulin G4 related sclerosing cholangitis, the management of dominant biliary strictures, and the role of ursodeoxycholic acid. In addition, the timing of liver transplantation in PSC remains difficult to predict with standard liver severity scores. In this review, we address these controversies and highlight the latest evidence base in the management of PSC." @default.
- W2299980382 created "2016-06-24" @default.
- W2299980382 creator A5033612328 @default.
- W2299980382 date "2016-01-01" @default.
- W2299980382 modified "2023-09-24" @default.
- W2299980382 title "Controversies in the management of primary sclerosing cholangitis" @default.
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- W2299980382 doi "https://doi.org/10.4254/wjh.v8.i5.265" @default.
- W2299980382 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4757649" @default.
- W2299980382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26925200" @default.
- W2299980382 hasPublicationYear "2016" @default.
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