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• W2300153721 abstract "A series of trans/trans and cis/cis fused-bis tetrahydrofuran compounds have been obtained stereoselectively in high yields via a one-pot operation involving the intramolecular haloetherification of (Z,Z)-diene diol 19a and (E,E)-diene disilylether 19d, respectively. This method was subsequently applied to the biomimetic-type synthesis of (±)- and (−)-aplysiallene. The inhibitory activities of these compounds and their bromodiene isomers toward Na+/K+ ATPase were determined in vitro, and gave IC50 values of approximately 15 μM in all cases." @default.
• W2300153721 created "2016-06-24" @default.
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• W2300153721 date "2015-10-07" @default.
• W2300153721 modified "2023-10-14" @default.
• W2300153721 title "Stereoselective Construction of 2,7-Disubstituted <i>fused</i>-Bis Tetrahydrofuran Skeletons: Biomimetic-Type Synthesis and Biological Evaluation of (±)- and (−)-Aplysiallene and Their Derivatives" @default.
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• W2300153721 doi "https://doi.org/10.1021/acs.joc.5b01882" @default.
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