Matches in SemOpenAlex for { <https://semopenalex.org/work/W2300322306> ?p ?o ?g. }
- W2300322306 endingPage "1054" @default.
- W2300322306 startingPage "1045" @default.
- W2300322306 abstract "ABSTRACTIntroduction: The progesterone receptor plays an essential role in uterine physiology and reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a valuable treatment option for hormone dependent conditions like uterine fibroids, which have a major impact on women’s quality of life. SPRMs offer potential for longer term medical treatment and thereby patients may avoid surgical intervention.Areas covered: The authors have reviewed the functional role of the progesterone receptor and its isoforms and their molecular mechanisms of action via genomic and non-genomic pathways. The current knowledge of the interaction of the PR and different SPRMs tested in clinical trials has been reviewed. The authors focused on pharmacological effects of selected SPRMs on the endometrium, their anti-proliferative action, and their suppression of bleeding. Potential underlying molecular mechanisms and the specific histological changes in the endometrium induced by SPRMs (PAEC; Progesterone rec..." @default.
- W2300322306 created "2016-06-24" @default.
- W2300322306 creator A5000333627 @default.
- W2300322306 creator A5030863406 @default.
- W2300322306 creator A5035159053 @default.
- W2300322306 creator A5049261308 @default.
- W2300322306 date "2016-05-14" @default.
- W2300322306 modified "2023-10-14" @default.
- W2300322306 title "Selective progesterone receptor modulators (SPRMs): progesterone receptor action, mode of action on the endometrium and treatment options in gynecological therapies" @default.
- W2300322306 cites W1910306760 @default.
- W2300322306 cites W1963928942 @default.
- W2300322306 cites W1969068003 @default.
- W2300322306 cites W1971532261 @default.
- W2300322306 cites W1972931629 @default.
- W2300322306 cites W1974761743 @default.
- W2300322306 cites W1975323045 @default.
- W2300322306 cites W1977213650 @default.
- W2300322306 cites W1981162986 @default.
- W2300322306 cites W1982066269 @default.
- W2300322306 cites W1984134696 @default.
- W2300322306 cites W1984592479 @default.
- W2300322306 cites W1984901643 @default.
- W2300322306 cites W1986914259 @default.
- W2300322306 cites W1987059285 @default.
- W2300322306 cites W1987183940 @default.
- W2300322306 cites W1988706650 @default.
- W2300322306 cites W1993750813 @default.
- W2300322306 cites W1994523467 @default.
- W2300322306 cites W1996100965 @default.
- W2300322306 cites W1996975584 @default.
- W2300322306 cites W1997430923 @default.
- W2300322306 cites W1999738495 @default.
- W2300322306 cites W2000777228 @default.
- W2300322306 cites W2001963326 @default.
- W2300322306 cites W2002975562 @default.
- W2300322306 cites W2004795545 @default.
- W2300322306 cites W2004857981 @default.
- W2300322306 cites W2005050501 @default.
- W2300322306 cites W2012863911 @default.
- W2300322306 cites W2015279480 @default.
- W2300322306 cites W2019278329 @default.
- W2300322306 cites W2019792229 @default.
- W2300322306 cites W2021270230 @default.
- W2300322306 cites W2025995094 @default.
- W2300322306 cites W2026392453 @default.
- W2300322306 cites W2027994881 @default.
- W2300322306 cites W2029983555 @default.
- W2300322306 cites W2031019135 @default.
- W2300322306 cites W2031512686 @default.
- W2300322306 cites W2032416959 @default.
- W2300322306 cites W2034601961 @default.
- W2300322306 cites W2034864360 @default.
- W2300322306 cites W2035439372 @default.
- W2300322306 cites W2040762618 @default.
- W2300322306 cites W2048574494 @default.
- W2300322306 cites W2049014099 @default.
- W2300322306 cites W2052734212 @default.
- W2300322306 cites W2055430160 @default.
- W2300322306 cites W2056876534 @default.
- W2300322306 cites W2058174458 @default.
- W2300322306 cites W2058537302 @default.
- W2300322306 cites W2060010595 @default.
- W2300322306 cites W2060920420 @default.
- W2300322306 cites W2062773135 @default.
- W2300322306 cites W2064443334 @default.
- W2300322306 cites W2071791804 @default.
- W2300322306 cites W2081506603 @default.
- W2300322306 cites W2082368668 @default.
- W2300322306 cites W2086867530 @default.
- W2300322306 cites W2090345475 @default.
- W2300322306 cites W2091903345 @default.
- W2300322306 cites W2095215260 @default.
- W2300322306 cites W2098019331 @default.
- W2300322306 cites W2102492167 @default.
- W2300322306 cites W2106587450 @default.
- W2300322306 cites W2109112573 @default.
- W2300322306 cites W2110046079 @default.
- W2300322306 cites W2111723376 @default.
- W2300322306 cites W2113190292 @default.
- W2300322306 cites W2113227671 @default.
- W2300322306 cites W2119638687 @default.
- W2300322306 cites W2120983951 @default.
- W2300322306 cites W2125336329 @default.
- W2300322306 cites W2125998976 @default.
- W2300322306 cites W2127228057 @default.
- W2300322306 cites W2128954873 @default.
- W2300322306 cites W2129725168 @default.
- W2300322306 cites W2131444472 @default.
- W2300322306 cites W2133341433 @default.
- W2300322306 cites W2133695286 @default.
- W2300322306 cites W2133700168 @default.
- W2300322306 cites W2134822865 @default.
- W2300322306 cites W2136812627 @default.
- W2300322306 cites W2137053400 @default.
- W2300322306 cites W2138053247 @default.
- W2300322306 cites W2139188294 @default.
- W2300322306 cites W2139307162 @default.
- W2300322306 cites W2140954107 @default.