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- W2300466987 abstract "In spite of advances in genetic evaluations through genomic information, using epigenetic information is still required. Recent advances in epigenetics indicates that most environmental factors (maybe all of them) affect the animal’s phenotype via epigenetics. Epigenetics includes alterations in the chromatin structure and collectively establishes different patterns of gene expression and silencing in the genome and is transferred during mitotic and meiotic divisions. In the present study, the mechanisms causing epigenetic regulations and the application of epigenetics in animal breeding are discussed, and new opportunities created by this interesting field have been explained. Three types of epialleles including permanent, temporary, and intergenerational, which can be used in epigenetic models, have also been proposed. Furthermore, using previous results of other researches, we first presented a model at the molecular level explaining the relationship between epigenetics, genetics, and environment in quantitative traits. According to this model, the interaction between epigenetics, genetics, and environment can improve the estimation of breeding values and reduce their biases." @default.
- W2300466987 created "2016-06-24" @default.
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- W2300466987 date "2015-02-15" @default.
- W2300466987 modified "2023-09-23" @default.
- W2300466987 title "Epigenetics: a new challenge in animal breeding." @default.
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