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- W2300688130 abstract "ObjectiveThis randomized, double blind trial was designed to compare the efficacy and safety of ezetimibe, a new cholesterol-lowering agent with atorvastatin (Lipitor), a potent cholesterolinhibitor derivative. MethodBetween September 2004 and March 2005, a total of 120 hyperlipidemic patients, aged 28-80 years, were randomized to receive ezetimibe 10 mg or atorvastatin 10 mg orally daily for 8 weeks after a 4-week washout phase and diet on NCEP step II. Mean changes of serum lipoproteins after 4 and 8 weeks of drug therapy were measured and compared in both groups of patients. ResultsEzetimibe reduced LDLc and total cholesterol by a mean of 27% and 16% compared with 32% and 24% for atorvastatin, respectively. The difference was not statistically significant. ConclusionEzetimibe and atorvastatin both reduced LDLc and TC with no statistically significant difference (Iranian Heart Journal 2007; 8 (1): 33-37)." @default.
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- W2300688130 date "2007-01-01" @default.
- W2300688130 modified "2023-09-23" @default.
- W2300688130 title "DOUBLE BLIND RANDOMIZED CLINICAL TRIAL OF EZETIMIBE VERSUS ATORVASTATIN IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA" @default.
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