FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2300698919> ?p ?o ?g. }

• W2300698919 abstract "Nelore is the major beef cattle breed in Brazil with more than 130 million heads. Genome-wide association studies (GWAS) are often used to associate markers and genomic regions to growth and meat quality traits that can be used to assist selection programs. An alternative methodology to traditional GWAS that involves the construction of gene network interactions, derived from results of several GWAS is the AWM (Association Weight Matrices)/PCIT (Partial Correlation and Information Theory). With the aim of evaluating the genetic architecture of Brazilian Nelore cattle, we used high-density SNP genotyping data (~770,000 SNP) from 780 Nelore animals comprising 34 half-sibling families derived from highly disseminated and unrelated sires from across Brazil. The AWM/PCIT methodology was employed to evaluate the genes that participate in a series of eight phenotypes related to growth and meat quality obtained from this Nelore sample. Our results indicate a lack of structuring between the individuals studied since principal component analyses were not able to differentiate families by its sires or by its ancestral lineages. The application of the AWM/PCIT methodology revealed a trio of transcription factors (comprising VDR, LHX9 and ZEB1) which in combination connected 66 genes through 359 edges and whose biological functions were inspected, some revealing to participate in biological growth processes in literature searches. The diversity of the Nelore sample studied is not high enough to differentiate among families neither by sires nor by using the available ancestral lineage information. The gene networks constructed from the AWM/PCIT methodology were a useful alternative in characterizing genes and gene networks that were allegedly influential in growth and meat quality traits in Nelore cattle." @default.
• W2300698919 created "2016-06-24" @default.
• W2300698919 creator A5000076284 @default.
• W2300698919 creator A5001082660 @default.
• W2300698919 creator A5006700249 @default.
• W2300698919 creator A5013737378 @default.
• W2300698919 creator A5015299929 @default.
• W2300698919 creator A5016943215 @default.
• W2300698919 creator A5026174887 @default.
• W2300698919 creator A5027245916 @default.
• W2300698919 creator A5029688490 @default.
• W2300698919 creator A5029804824 @default.
• W2300698919 creator A5035040549 @default.
• W2300698919 creator A5038960649 @default.
• W2300698919 creator A5039467912 @default.
• W2300698919 creator A5042002798 @default.
• W2300698919 creator A5047289070 @default.
• W2300698919 creator A5055148511 @default.
• W2300698919 creator A5058198464 @default.
• W2300698919 creator A5058230865 @default.
• W2300698919 creator A5063403499 @default.
• W2300698919 creator A5067457955 @default.
• W2300698919 creator A5074319488 @default.
• W2300698919 creator A5076241242 @default.
• W2300698919 creator A5079898288 @default.
• W2300698919 creator A5086267943 @default.
• W2300698919 creator A5086374209 @default.
• W2300698919 creator A5087565933 @default.
• W2300698919 creator A5091575278 @default.
• W2300698919 date "2016-03-15" @default.
• W2300698919 modified "2023-10-16" @default.
• W2300698919 title "Genomic structure and marker-derived gene networks for growth and meat quality traits of Brazilian Nelore beef cattle" @default.
• W2300698919 cites W155661153 @default.
• W2300698919 cites W1660610441 @default.
• W2300698919 cites W1726567374 @default.
• W2300698919 cites W177285336 @default.
• W2300698919 cites W1928998639 @default.
• W2300698919 cites W1964189009 @default.
• W2300698919 cites W1975728012 @default.
• W2300698919 cites W1975815877 @default.
• W2300698919 cites W1976630325 @default.
• W2300698919 cites W1982733535 @default.
• W2300698919 cites W1991404519 @default.
• W2300698919 cites W1994689597 @default.
• W2300698919 cites W1999047841 @default.
• W2300698919 cites W1999871368 @default.
• W2300698919 cites W2002155339 @default.
• W2300698919 cites W2005935256 @default.
• W2300698919 cites W2007212414 @default.
• W2300698919 cites W2019147681 @default.
• W2300698919 cites W2019866305 @default.
• W2300698919 cites W2021098202 @default.
• W2300698919 cites W2021828797 @default.
• W2300698919 cites W2024027525 @default.
• W2300698919 cites W2032578950 @default.
• W2300698919 cites W2033838456 @default.
• W2300698919 cites W2036300567 @default.
• W2300698919 cites W2038963685 @default.
• W2300698919 cites W2040680124 @default.
• W2300698919 cites W2040810001 @default.
• W2300698919 cites W2044045116 @default.
• W2300698919 cites W2046434400 @default.
• W2300698919 cites W2047524069 @default.
• W2300698919 cites W2053169778 @default.
• W2300698919 cites W2055014245 @default.
• W2300698919 cites W2056622446 @default.
• W2300698919 cites W2057328004 @default.
• W2300698919 cites W2057751649 @default.
• W2300698919 cites W2058441973 @default.
• W2300698919 cites W2060870711 @default.
• W2300698919 cites W2066130584 @default.
• W2300698919 cites W2067715889 @default.
• W2300698919 cites W2067839296 @default.
• W2300698919 cites W2069325782 @default.
• W2300698919 cites W2069661419 @default.
• W2300698919 cites W2075406901 @default.
• W2300698919 cites W2083497058 @default.
• W2300698919 cites W2085238796 @default.
• W2300698919 cites W2087859070 @default.
• W2300698919 cites W2091071679 @default.
• W2300698919 cites W2091895066 @default.
• W2300698919 cites W2097596314 @default.
• W2300698919 cites W2101751002 @default.
• W2300698919 cites W2107084703 @default.
• W2300698919 cites W2110018909 @default.
• W2300698919 cites W2113028019 @default.
• W2300698919 cites W2113932013 @default.
• W2300698919 cites W2117118135 @default.
• W2300698919 cites W2117470934 @default.
• W2300698919 cites W211770871 @default.
• W2300698919 cites W2122455121 @default.
• W2300698919 cites W2126885653 @default.
• W2300698919 cites W2127457459 @default.
• W2300698919 cites W2134586291 @default.
• W2300698919 cites W2134958293 @default.
• W2300698919 cites W2137556019 @default.
• W2300698919 cites W2138345444 @default.
• W2300698919 cites W2146367124 @default.
• W2300698919 cites W2149019022 @default.
• W2300698919 cites W2150806217 @default.

• next