FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2300717780> ?p ?o ?g. }

• W2300717780 endingPage "160" @default.
• W2300717780 startingPage "148" @default.
• W2300717780 abstract "An extension of our previous research work has resulted in a number of new ATP-competitive CK2 inhibitors that have been identified among 4-aminothieno[2,3-d]pyrimidine derivatives. The most active compounds obtained in the course of the research are 3-(5-p-tolyl-thieno[2,3-d]pyrimidin-4-ylamino)-benzoic acid, 5e (NHTP23, IC50 = 0.01 μM), 3-(5-phenyl-thieno[2,3-d]pyrimidin-4-ylamino)-benzoic acid, 5g (NHTP25, IC50 = 0.065 μM) and 3-(6-methyl-5-phenyl-thieno[2,3-d]pyrimidin-4-ylamino)-benzoic acid, 5n (NHTP33, IC50 = 0.008 μM). Structure-activity relationships of the tested 4-aminothieno[2,3-d]pyrimidine derivatives have been studied and their binding mode with ATP-acceptor site of CK2 has been proposed. A negative effect of intramolecular hydrogen bonding in the compounds' structure is discussed." @default.
• W2300717780 created "2016-06-24" @default.
• W2300717780 creator A5003814605 @default.
• W2300717780 creator A5008058777 @default.
• W2300717780 creator A5012505413 @default.
• W2300717780 creator A5033287592 @default.
• W2300717780 creator A5048040998 @default.
• W2300717780 creator A5056981757 @default.
• W2300717780 creator A5058835486 @default.
• W2300717780 creator A5064040362 @default.
• W2300717780 creator A5076639541 @default.
• W2300717780 date "2016-06-01" @default.
• W2300717780 modified "2023-09-27" @default.
• W2300717780 title "Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno[2,3-d]pyrimidines" @default.
• W2300717780 cites W1677175288 @default.
• W2300717780 cites W1967173776 @default.
• W2300717780 cites W1972361002 @default.
• W2300717780 cites W2016011980 @default.
• W2300717780 cites W2022979136 @default.
• W2300717780 cites W2048736992 @default.
• W2300717780 cites W2049502419 @default.
• W2300717780 cites W2053045007 @default.
• W2300717780 cites W2067585469 @default.
• W2300717780 cites W2077964369 @default.
• W2300717780 cites W2085173493 @default.
• W2300717780 cites W2087471640 @default.
• W2300717780 cites W2088938650 @default.
• W2300717780 cites W2090762415 @default.
• W2300717780 cites W2092063610 @default.
• W2300717780 cites W2095510836 @default.
• W2300717780 cites W2105668062 @default.
• W2300717780 cites W2140074237 @default.
• W2300717780 cites W2141158380 @default.
• W2300717780 cites W2172033858 @default.
• W2300717780 cites W2172171459 @default.
• W2300717780 cites W2172175555 @default.
• W2300717780 cites W2326610434 @default.
• W2300717780 doi "https://doi.org/10.1016/j.ejmech.2016.03.004" @default.
• W2300717780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27017545" @default.
• W2300717780 hasPublicationYear "2016" @default.
• W2300717780 type Work @default.
• W2300717780 sameAs 2300717780 @default.
• W2300717780 citedByCount "18" @default.
• W2300717780 countsByYear W23007177802017 @default.
• W2300717780 countsByYear W23007177802018 @default.
• W2300717780 countsByYear W23007177802019 @default.
• W2300717780 countsByYear W23007177802020 @default.
• W2300717780 countsByYear W23007177802022 @default.
• W2300717780 countsByYear W23007177802023 @default.
• W2300717780 crossrefType "journal-article" @default.
• W2300717780 hasAuthorship W2300717780A5003814605 @default.
• W2300717780 hasAuthorship W2300717780A5008058777 @default.
• W2300717780 hasAuthorship W2300717780A5012505413 @default.
• W2300717780 hasAuthorship W2300717780A5033287592 @default.
• W2300717780 hasAuthorship W2300717780A5048040998 @default.
• W2300717780 hasAuthorship W2300717780A5056981757 @default.
• W2300717780 hasAuthorship W2300717780A5058835486 @default.
• W2300717780 hasAuthorship W2300717780A5064040362 @default.
• W2300717780 hasAuthorship W2300717780A5076639541 @default.
• W2300717780 hasConcept C112887158 @default.
• W2300717780 hasConcept C155647269 @default.
• W2300717780 hasConcept C178790620 @default.
• W2300717780 hasConcept C181199279 @default.
• W2300717780 hasConcept C185592680 @default.
• W2300717780 hasConcept C202751555 @default.
• W2300717780 hasConcept C2777752497 @default.
• W2300717780 hasConcept C2778844314 @default.
• W2300717780 hasConcept C2779321679 @default.
• W2300717780 hasConcept C32909587 @default.
• W2300717780 hasConcept C41183919 @default.
• W2300717780 hasConcept C55493867 @default.
• W2300717780 hasConcept C71240020 @default.
• W2300717780 hasConcept C75079739 @default.
• W2300717780 hasConceptScore W2300717780C112887158 @default.
• W2300717780 hasConceptScore W2300717780C155647269 @default.
• W2300717780 hasConceptScore W2300717780C178790620 @default.
• W2300717780 hasConceptScore W2300717780C181199279 @default.
• W2300717780 hasConceptScore W2300717780C185592680 @default.
• W2300717780 hasConceptScore W2300717780C202751555 @default.
• W2300717780 hasConceptScore W2300717780C2777752497 @default.
• W2300717780 hasConceptScore W2300717780C2778844314 @default.
• W2300717780 hasConceptScore W2300717780C2779321679 @default.
• W2300717780 hasConceptScore W2300717780C32909587 @default.
• W2300717780 hasConceptScore W2300717780C41183919 @default.
• W2300717780 hasConceptScore W2300717780C55493867 @default.
• W2300717780 hasConceptScore W2300717780C71240020 @default.
• W2300717780 hasConceptScore W2300717780C75079739 @default.
• W2300717780 hasFunder F4320322850 @default.
• W2300717780 hasLocation W23007177801 @default.
• W2300717780 hasLocation W23007177802 @default.
• W2300717780 hasOpenAccess W2300717780 @default.
• W2300717780 hasPrimaryLocation W23007177801 @default.
• W2300717780 hasRelatedWork W1560314682 @default.
• W2300717780 hasRelatedWork W1781154698 @default.
• W2300717780 hasRelatedWork W2006252551 @default.
• W2300717780 hasRelatedWork W2041974313 @default.
• W2300717780 hasRelatedWork W2075292276 @default.
• W2300717780 hasRelatedWork W2090070712 @default.

• next