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- W2300749209 abstract "Obesity, particularly intra-abdominal (visceral) obesity, is a leading cause of cardiovascular disease (CVD), insulin resistance, type 2 diabetes, dyslipidaemia, inflammation and thrombosis. A useful indicator for visceral fat is waist circumference, which is associated with all-cause mortality. Pro-inflammatory adipokines play a causal role in the development of pathologies associated with insulin resistance, type 2 diabetes and CVD. In addition to established anti-obesity therapies, namely orlistat and sibutramine, a new type of agent that inhibits the cannabinoid receptor (CB 1 ) is advanced in development to reduce appetite and act predominantly against intra-abdominal adiposity." @default.
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- W2300749209 title "Thinking around abdominal obesity and cardiovascular risk : review" @default.
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