FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2300814852> ?p ?o ?g. }

• W2300814852 endingPage "537" @default.
• W2300814852 startingPage "531" @default.
• W2300814852 abstract "Macrolides are often used to treat and control bacterial pathogens causing respiratory disease in pigs. This study analyzed the whole genome sequences of one clinical isolate of Actinobacillus pleuropneumoniae, Haemophilus parasuis, Pasteurella multocida, and Bordetella bronchiseptica, all isolated from Australian pigs to identify the mechanism underlying the elevated minimum inhibitory concentrations (MICs) for erythromycin, tilmicosin, or tulathromycin. The H. parasuis assembled genome had a nucleotide transition at position 2059 (A to G) in the six copies of the 23S rRNA gene. This mutation has previously been associated with macrolide resistance but this is the first reported mechanism associated with elevated macrolide MICs in H. parasuis. There was no known macrolide resistance mechanism identified in the other three bacterial genomes. However, strA and sul2, aminoglycoside and sulfonamide resistance genes, respectively, were detected in one contiguous sequence (contig 1) of A. pleuropneumoniae assembled genome. This contig was identical to plasmids previously identified in Pasteurellaceae. This study has provided one possible explanation of elevated MICs to macrolides in H. parasuis. Further studies are necessary to clarify the mechanism causing the unexplained macrolide resistance in other Australian pig respiratory pathogens including the role of efflux systems, which were detected in all analyzed genomes." @default.
• W2300814852 created "2016-06-24" @default.
• W2300814852 creator A5043686696 @default.
• W2300814852 creator A5050305550 @default.
• W2300814852 creator A5058781236 @default.
• W2300814852 creator A5068675209 @default.
• W2300814852 date "2016-10-01" @default.
• W2300814852 modified "2023-09-27" @default.
• W2300814852 title "Whole Genome Sequence Analysis of Pig Respiratory Bacterial Pathogens with Elevated Minimum Inhibitory Concentrations for Macrolides" @default.
• W2300814852 cites W1559472018 @default.
• W2300814852 cites W1748215068 @default.
• W2300814852 cites W1979708765 @default.
• W2300814852 cites W1991666823 @default.
• W2300814852 cites W1995752637 @default.
• W2300814852 cites W2004548026 @default.
• W2300814852 cites W2020409760 @default.
• W2300814852 cites W2022470204 @default.
• W2300814852 cites W2028832063 @default.
• W2300814852 cites W2029252255 @default.
• W2300814852 cites W2033064801 @default.
• W2300814852 cites W2039694361 @default.
• W2300814852 cites W2053270787 @default.
• W2300814852 cites W2057289514 @default.
• W2300814852 cites W2063300627 @default.
• W2300814852 cites W2067312026 @default.
• W2300814852 cites W2085154179 @default.
• W2300814852 cites W2095959951 @default.
• W2300814852 cites W2096597147 @default.
• W2300814852 cites W2099837668 @default.
• W2300814852 cites W2104500040 @default.
• W2300814852 cites W2106000944 @default.
• W2300814852 cites W2109514676 @default.
• W2300814852 cites W2112189687 @default.
• W2300814852 cites W2118688136 @default.
• W2300814852 cites W2119845188 @default.
• W2300814852 cites W2124557658 @default.
• W2300814852 cites W2125583150 @default.
• W2300814852 cites W2128880918 @default.
• W2300814852 cites W2134852597 @default.
• W2300814852 cites W2140929743 @default.
• W2300814852 cites W2144288776 @default.
• W2300814852 cites W2151308994 @default.
• W2300814852 cites W2152511939 @default.
• W2300814852 cites W2153328144 @default.
• W2300814852 cites W2156521009 @default.
• W2300814852 cites W4211233303 @default.
• W2300814852 doi "https://doi.org/10.1089/mdr.2015.0214" @default.
• W2300814852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26981707" @default.
• W2300814852 hasPublicationYear "2016" @default.
• W2300814852 type Work @default.
• W2300814852 sameAs 2300814852 @default.
• W2300814852 citedByCount "10" @default.
• W2300814852 countsByYear W23008148522016 @default.
• W2300814852 countsByYear W23008148522017 @default.
• W2300814852 countsByYear W23008148522018 @default.
• W2300814852 countsByYear W23008148522019 @default.
• W2300814852 countsByYear W23008148522020 @default.
• W2300814852 countsByYear W23008148522022 @default.
• W2300814852 countsByYear W23008148522023 @default.
• W2300814852 crossrefType "journal-article" @default.
• W2300814852 hasAuthorship W2300814852A5043686696 @default.
• W2300814852 hasAuthorship W2300814852A5050305550 @default.
• W2300814852 hasAuthorship W2300814852A5058781236 @default.
• W2300814852 hasAuthorship W2300814852A5068675209 @default.
• W2300814852 hasConcept C10389963 @default.
• W2300814852 hasConcept C104317684 @default.
• W2300814852 hasConcept C141231307 @default.
• W2300814852 hasConcept C159047783 @default.
• W2300814852 hasConcept C22744801 @default.
• W2300814852 hasConcept C24432333 @default.
• W2300814852 hasConcept C2776231263 @default.
• W2300814852 hasConcept C2776402342 @default.
• W2300814852 hasConcept C2776796551 @default.
• W2300814852 hasConcept C2776925733 @default.
• W2300814852 hasConcept C2777107318 @default.
• W2300814852 hasConcept C2777154767 @default.
• W2300814852 hasConcept C2780861368 @default.
• W2300814852 hasConcept C40749294 @default.
• W2300814852 hasConcept C501593827 @default.
• W2300814852 hasConcept C523546767 @default.
• W2300814852 hasConcept C54355233 @default.
• W2300814852 hasConcept C67705224 @default.
• W2300814852 hasConcept C86803240 @default.
• W2300814852 hasConcept C88478588 @default.
• W2300814852 hasConcept C89423630 @default.
• W2300814852 hasConceptScore W2300814852C10389963 @default.
• W2300814852 hasConceptScore W2300814852C104317684 @default.
• W2300814852 hasConceptScore W2300814852C141231307 @default.
• W2300814852 hasConceptScore W2300814852C159047783 @default.
• W2300814852 hasConceptScore W2300814852C22744801 @default.
• W2300814852 hasConceptScore W2300814852C24432333 @default.
• W2300814852 hasConceptScore W2300814852C2776231263 @default.
• W2300814852 hasConceptScore W2300814852C2776402342 @default.
• W2300814852 hasConceptScore W2300814852C2776796551 @default.
• W2300814852 hasConceptScore W2300814852C2776925733 @default.
• W2300814852 hasConceptScore W2300814852C2777107318 @default.
• W2300814852 hasConceptScore W2300814852C2777154767 @default.
• W2300814852 hasConceptScore W2300814852C2780861368 @default.

• next