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- W230089096 abstract "This chapter discusses the effects of intra-aortic infusions of hypertonic NaCl on hypovolemic shock. It presents a few experiments that were performed on 22 mongrel dogs. Ten of these dogs received an intra-aortic infusion at 30 min post-zero. Blood pressure, blood gases, and survival were recorded. Osmotic titration of pulmonary artery plasma showed a very highly significant difference between intra-aortic and intravenous infusions. During an intravenous infusion, pulmonary plasma osmolarity rises 2.5 times higher than it does during an intra-aortic infusion. After the end of the infusions, osmolarity drops back to very near control levels, after an intra-aortic infusion, but remains at a significantly increased level, following an intravenous infusion. The six intravenously infused dogs in this group survived indefinitely, while the six intra-aortically infused dogs died within 36 h of zero-time. These experiments demonstrated that a high osmolar concentration must be reached in the pulmonary circulation to elicit the general response, which leads to indefinite survival, even though an intra-aortic infusion is capable of producing a transient recovery of blood pressure." @default.
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- W230089096 date "1981-01-01" @default.
- W230089096 modified "2023-09-23" @default.
- W230089096 title "INTRA-AORTIC INFUSIONS OF HYPERTONIC NaCl DO NOT REVERSE HYPOVOLEMIC SHOCK" @default.
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- W230089096 doi "https://doi.org/10.1016/b978-0-08-027347-1.50050-5" @default.
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