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• W2300945024 abstract "Gene-targeting strategies based on nucleic acid have opened a new era with the development of potent and effective gene intervention strategies, such as DNAzymes, ribozymes, small interfering RNAs (siRNAs), antisense oligonucleotides (ASOs), aptamers, decoys, etc. These technologies have been examined in the setting of clinical trials, and several have recently made the successful transition from basic research to clinical trials. This chapter discusses progress made in these technologies, mainly focusing on Dzs and siRNAs, because these are poised to play an integral role in antigene therapies in the future." @default.
• W2300945024 created "2016-06-24" @default.
• W2300945024 creator A5010973941 @default.
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• W2300945024 date "2016-03-16" @default.
• W2300945024 modified "2023-09-27" @default.
• W2300945024 title "Small-molecule Nucleic-acid-based Gene-silencing Strategies" @default.
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• W2300945024 doi "https://doi.org/10.5772/62137" @default.
• W2300945024 hasPublicationYear "2016" @default.
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