FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2301092011> ?p ?o ?g. }

• W2301092011 endingPage "169" @default.
• W2301092011 startingPage "159" @default.
• W2301092011 abstract "The use of valved stents for minimally invasive replacement of semilunar heart valves is expected to change the extracellular matrix and mechanical function of the native artery and may thus impair long-term functionality of the implant. Here we investigate the impact of the stent on matrix remodeling of the pulmonary artery in a sheep model, focusing on matrix composition and collagen (re)orientation of the host tissue. Ovine native pulmonary arteries were harvested 8 (n = 2), 16 (n = 4) and 24 (n = 2) weeks after transapical implantation of self-expandable stented heart valves. Second harmonic generation (SHG) microscopy was used to assess the collagen (re)orientation of fresh tissue samples. The collagen and elastin content was quantified using biochemical assays. SHG microscopy revealed regional differences in collagen organization in all explants. In the adventitial layer of the arterial wall far distal to the stent (considered as the control tissue), we observed wavy collagen fibers oriented in the circumferential direction. These circumferential fibers were more straightened in the adventitial layer located behind the stent. On the luminal side of the wall behind the stent, collagen fibers were aligned along the stent struts and randomly oriented between the struts. Immediately distal to the stent, however, fibers on both the luminal and the adventitial side of the wall were oriented in the axial direction, demonstrating the stent impact on the collagen structure of surrounding arterial tissues. Collagen orientation patterns did not change with implantation time, and biochemical analyses showed no changes in the trend of collagen and elastin content with implantation time or location of the vascular wall. We hypothesize that the collagen fibers on the adventitial side of the arterial wall and behind the stent straighten in response to the arterial stretch caused by oversizing of the stent. However, the collagen organization on the luminal side suggests that stent-induced remodeling is dominated by contact guidance." @default.
• W2301092011 created "2016-06-24" @default.
• W2301092011 creator A5015386252 @default.
• W2301092011 creator A5019165155 @default.
• W2301092011 creator A5032481936 @default.
• W2301092011 creator A5037238098 @default.
• W2301092011 creator A5044939299 @default.
• W2301092011 date "2016-01-01" @default.
• W2301092011 modified "2023-10-14" @default.
• W2301092011 title "Collagen Matrix Remodeling in Stented Pulmonary Arteries after Transapical Heart Valve Replacement" @default.
• W2301092011 cites W1522824862 @default.
• W2301092011 cites W1827569473 @default.
• W2301092011 cites W1979968811 @default.
• W2301092011 cites W1984484225 @default.
• W2301092011 cites W1984804049 @default.
• W2301092011 cites W1988066887 @default.
• W2301092011 cites W1992147175 @default.
• W2301092011 cites W2001770837 @default.
• W2301092011 cites W2004104615 @default.
• W2301092011 cites W2016347117 @default.
• W2301092011 cites W2017560892 @default.
• W2301092011 cites W2028115482 @default.
• W2301092011 cites W2028181518 @default.
• W2301092011 cites W2036188479 @default.
• W2301092011 cites W2044021383 @default.
• W2301092011 cites W2045601635 @default.
• W2301092011 cites W2050535216 @default.
• W2301092011 cites W2053908272 @default.
• W2301092011 cites W2054844811 @default.
• W2301092011 cites W2067377927 @default.
• W2301092011 cites W2067869939 @default.
• W2301092011 cites W2067876811 @default.
• W2301092011 cites W2074147017 @default.
• W2301092011 cites W2074352949 @default.
• W2301092011 cites W2075717479 @default.
• W2301092011 cites W2090136057 @default.
• W2301092011 cites W2090648368 @default.
• W2301092011 cites W2093770019 @default.
• W2301092011 cites W2096295381 @default.
• W2301092011 cites W2100139763 @default.
• W2301092011 cites W2127722806 @default.
• W2301092011 cites W2134276490 @default.
• W2301092011 cites W2134926355 @default.
• W2301092011 cites W2141582798 @default.
• W2301092011 cites W2149753712 @default.
• W2301092011 cites W2151149598 @default.
• W2301092011 cites W2159994931 @default.
• W2301092011 cites W2162133780 @default.
• W2301092011 cites W2171253876 @default.
• W2301092011 cites W2171332976 @default.
• W2301092011 cites W2343073204 @default.
• W2301092011 cites W368681593 @default.
• W2301092011 doi "https://doi.org/10.1159/000442521" @default.
• W2301092011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5296926" @default.
• W2301092011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26989895" @default.
• W2301092011 hasPublicationYear "2016" @default.
• W2301092011 type Work @default.
• W2301092011 sameAs 2301092011 @default.
• W2301092011 citedByCount "17" @default.
• W2301092011 countsByYear W23010920112016 @default.
• W2301092011 countsByYear W23010920112018 @default.
• W2301092011 countsByYear W23010920112019 @default.
• W2301092011 countsByYear W23010920112020 @default.
• W2301092011 countsByYear W23010920112021 @default.
• W2301092011 countsByYear W23010920112022 @default.
• W2301092011 crossrefType "journal-article" @default.
• W2301092011 hasAuthorship W2301092011A5015386252 @default.
• W2301092011 hasAuthorship W2301092011A5019165155 @default.
• W2301092011 hasAuthorship W2301092011A5032481936 @default.
• W2301092011 hasAuthorship W2301092011A5037238098 @default.
• W2301092011 hasAuthorship W2301092011A5044939299 @default.
• W2301092011 hasBestOaLocation W23010920111 @default.
• W2301092011 hasConcept C105702510 @default.
• W2301092011 hasConcept C106487976 @default.
• W2301092011 hasConcept C136229726 @default.
• W2301092011 hasConcept C141071460 @default.
• W2301092011 hasConcept C142724271 @default.
• W2301092011 hasConcept C159985019 @default.
• W2301092011 hasConcept C164705383 @default.
• W2301092011 hasConcept C185592680 @default.
• W2301092011 hasConcept C189165786 @default.
• W2301092011 hasConcept C192562407 @default.
• W2301092011 hasConcept C2776229121 @default.
• W2301092011 hasConcept C2776820930 @default.
• W2301092011 hasConcept C2778583881 @default.
• W2301092011 hasConcept C2779869378 @default.
• W2301092011 hasConcept C2780028357 @default.
• W2301092011 hasConcept C2780940725 @default.
• W2301092011 hasConcept C2781411149 @default.
• W2301092011 hasConcept C71924100 @default.
• W2301092011 hasConcept C86803240 @default.
• W2301092011 hasConcept C95444343 @default.
• W2301092011 hasConceptScore W2301092011C105702510 @default.
• W2301092011 hasConceptScore W2301092011C106487976 @default.
• W2301092011 hasConceptScore W2301092011C136229726 @default.
• W2301092011 hasConceptScore W2301092011C141071460 @default.
• W2301092011 hasConceptScore W2301092011C142724271 @default.
• W2301092011 hasConceptScore W2301092011C159985019 @default.

• next