FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2301277816> ?p ?o ?g. }

• W2301277816 endingPage "1200" @default.
• W2301277816 startingPage "1190" @default.
• W2301277816 abstract "To map the 3-dimensional (3D) strain of the optic nerve head (ONH) in vivo after intraocular pressure (IOP) lowering by trabeculectomy (TE) and to establish associations between ONH strain and retinal sensitivity.Observational case series.Nine patients with primary open-angle glaucoma (POAG) and 3 normal controls.The ONHs of 9 subjects with POAG (pre-TE IOP: 25.3±13.9 mmHg; post-TE IOP: 11.8±8.6 mmHg) were imaged (1 eye per subject) using optical coherence tomography (OCT) (Heidelberg Spectralis, Heidelberg Engineering GmbH, Heidelberg, Germany) before (<21 days) and after (<50 days) TE. The imaging protocol was repeated for 3 controls in whom IOP was not altered. In each post-TE OCT volume, 4 tissues were manually segmented (prelamina, choroid, sclera, and lamina cribrosa [LC]). For each ONH, a 3D tracking algorithm was applied to both post- and pre-TE OCT volumes to extract IOP-induced 3D displacements at segmented nodes. Displacements were filtered, smoothed, and processed to extract 3D strain relief (the amount of tissue deformation relieved after TE). Strain relief was compared with measures of retinal sensitivity from visual field testing.Three-dimensional ONH displacements and strain relief.On average, strain relief (averaged or effective component) in the glaucoma ONHs (8.6%) due to TE was higher than that measured in the normal controls (1.07%). We found no associations between the magnitude of IOP decrease and the LC strain relief (P > 0.05), suggesting biomechanical variability across subjects. The LC displaced posteriorly, anteriorly, or not at all. Furthermore, we found linear associations between retinal sensitivity and LC effective strain relief (P < 0.001; high strain relief associated with low retinal sensitivity).We demonstrate that ONH displacements and strains can be measured in vivo and that TE can relieve ONH strains. Our data suggest a wide variability in ONH biomechanics in the subjects examined in this study. We further demonstrate associations between LC effective strain relief and retinal sensitivity." @default.
• W2301277816 created "2016-06-24" @default.
• W2301277816 creator A5000947643 @default.
• W2301277816 creator A5003431129 @default.
• W2301277816 creator A5011443225 @default.
• W2301277816 creator A5018267451 @default.
• W2301277816 creator A5022464374 @default.
• W2301277816 creator A5028418397 @default.
• W2301277816 creator A5034476894 @default.
• W2301277816 creator A5035391535 @default.
• W2301277816 creator A5051614504 @default.
• W2301277816 creator A5054878311 @default.
• W2301277816 creator A5078113273 @default.
• W2301277816 date "2016-06-01" @default.
• W2301277816 modified "2023-10-15" @default.
• W2301277816 title "In Vivo 3-Dimensional Strain Mapping of the Optic Nerve Head Following Intraocular Pressure Lowering by Trabeculectomy" @default.
• W2301277816 cites W1820257239 @default.
• W2301277816 cites W1965358032 @default.
• W2301277816 cites W1969758088 @default.
• W2301277816 cites W1973199282 @default.
• W2301277816 cites W1974806416 @default.
• W2301277816 cites W1978097677 @default.
• W2301277816 cites W1982537788 @default.
• W2301277816 cites W1984618569 @default.
• W2301277816 cites W1987041755 @default.
• W2301277816 cites W1987502158 @default.
• W2301277816 cites W1991821214 @default.
• W2301277816 cites W2008578231 @default.
• W2301277816 cites W2038047187 @default.
• W2301277816 cites W2043817890 @default.
• W2301277816 cites W2047268748 @default.
• W2301277816 cites W2053567524 @default.
• W2301277816 cites W2055269249 @default.
• W2301277816 cites W2060287042 @default.
• W2301277816 cites W2065969837 @default.
• W2301277816 cites W2067678530 @default.
• W2301277816 cites W2070713040 @default.
• W2301277816 cites W2072186463 @default.
• W2301277816 cites W2076772578 @default.
• W2301277816 cites W2077022004 @default.
• W2301277816 cites W2092839363 @default.
• W2301277816 cites W2093007223 @default.
• W2301277816 cites W2093525192 @default.
• W2301277816 cites W2096480061 @default.
• W2301277816 cites W2097795807 @default.
• W2301277816 cites W2099379703 @default.
• W2301277816 cites W2100556262 @default.
• W2301277816 cites W2101176008 @default.
• W2301277816 cites W2104788465 @default.
• W2301277816 cites W2109097075 @default.
• W2301277816 cites W2118644586 @default.
• W2301277816 cites W2120133270 @default.
• W2301277816 cites W2121357494 @default.
• W2301277816 cites W2131030892 @default.
• W2301277816 cites W2135435567 @default.
• W2301277816 cites W2152341218 @default.
• W2301277816 cites W2161094362 @default.
• W2301277816 cites W2162145193 @default.
• W2301277816 cites W2272793699 @default.
• W2301277816 cites W2276000118 @default.
• W2301277816 cites W2314137183 @default.
• W2301277816 cites W302579078 @default.
• W2301277816 doi "https://doi.org/10.1016/j.ophtha.2016.02.008" @default.
• W2301277816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26992836" @default.
• W2301277816 hasPublicationYear "2016" @default.
• W2301277816 type Work @default.
• W2301277816 sameAs 2301277816 @default.
• W2301277816 citedByCount "72" @default.
• W2301277816 countsByYear W23012778162016 @default.
• W2301277816 countsByYear W23012778162017 @default.
• W2301277816 countsByYear W23012778162018 @default.
• W2301277816 countsByYear W23012778162019 @default.
• W2301277816 countsByYear W23012778162020 @default.
• W2301277816 countsByYear W23012778162021 @default.
• W2301277816 countsByYear W23012778162022 @default.
• W2301277816 countsByYear W23012778162023 @default.
• W2301277816 crossrefType "journal-article" @default.
• W2301277816 hasAuthorship W2301277816A5000947643 @default.
• W2301277816 hasAuthorship W2301277816A5003431129 @default.
• W2301277816 hasAuthorship W2301277816A5011443225 @default.
• W2301277816 hasAuthorship W2301277816A5018267451 @default.
• W2301277816 hasAuthorship W2301277816A5022464374 @default.
• W2301277816 hasAuthorship W2301277816A5028418397 @default.
• W2301277816 hasAuthorship W2301277816A5034476894 @default.
• W2301277816 hasAuthorship W2301277816A5035391535 @default.
• W2301277816 hasAuthorship W2301277816A5051614504 @default.
• W2301277816 hasAuthorship W2301277816A5054878311 @default.
• W2301277816 hasAuthorship W2301277816A5078113273 @default.
• W2301277816 hasConcept C105702510 @default.
• W2301277816 hasConcept C118487528 @default.
• W2301277816 hasConcept C120665830 @default.
• W2301277816 hasConcept C121332964 @default.
• W2301277816 hasConcept C2776694393 @default.
• W2301277816 hasConcept C2777093970 @default.
• W2301277816 hasConcept C2777100477 @default.
• W2301277816 hasConcept C2777824320 @default.
• W2301277816 hasConcept C2777989353 @default.
• W2301277816 hasConcept C2778022156 @default.

• next