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- W2302002935 abstract "Objective To assess the value of galactaomannan(GM) detection in three kinds of fluid samples from rat model of invasive pulmonary aspergillosis(IPA).Methods Collected the samples of bronchoalveolar lavage fluid(BALF),plasma and urine for GM detection after the IPA model was established.At the same time,the lung tissue was collected for pathological examination and mycology culture.Results After early infection for 1,3 and 5 days,the average sensitivity of GM test of plasma in experimental group were 58.30%,66.67% and 83.33%,while,the GM test of BALF were 66.67%,91.67% and 100%,respectively.That had significant differences compared with control group.All of the 72 rats' GM value in plasma and BALF samples had the sensitivity for 69.44%,86.11%,and both the specificity for 100%.Meanwhile,the positive predictive value were both 100%,and the negative predictive value were 68.57% and 82.76%,respectively.There were 5 positive GM value in all urine specimens detection with the sensitivity was 13.89%,and the specificity was 100%.All the GM value trended to rise with the increase of infection days.Conclusion GM detection in BALF and plasma may contribute to the early diagnosis of IPA." @default.
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- W2302002935 date "2010-01-01" @default.
- W2302002935 modified "2023-09-28" @default.
- W2302002935 title "Significance of galactaomannan detection in three kinds of fluid samples from rat model of invasive pulmonary aspergillosis" @default.
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