FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2302483558> ?p ?o ?g. }

• W2302483558 endingPage "i939" @default.
• W2302483558 startingPage "i939" @default.
• W2302483558 abstract "<b>Objectives</b> To systematically review studies investigating the prevalence of antibiotic resistance in urinary tract infections caused by <i>Escherichia coli</i> in children and, when appropriate, to meta-analyse the relation between previous antibiotics prescribed in primary care and resistance. <b>Design and data analysis</b> Systematic review and meta-analysis. Pooled percentage prevalence of resistance to the most commonly used antibiotics in children in primary care, stratified by the OECD (Organisation for Economic Co-operation and Development) status of the study country. Random effects meta-analysis was used to quantify the association between previous exposure to antibiotics in primary care and resistance. <b>Data sources</b> Observational and experimental studies identified through Medline, Embase, Cochrane, and ISI Web of Knowledge databases, searched for articles published up to October 2015. <b>Eligibility criteria for selecting studies</b> Studies were eligible if they investigated and reported resistance in community acquired urinary tract infection in children and young people aged 0-17. Electronic searches with MeSH terms and text words identified 3115 papers. Two independent reviewers assessed study quality and performed data extraction. <b>Results</b> 58 observational studies investigated 77 783 <i>E coli</i> isolates in urine. In studies from OECD countries, the pooled prevalence of resistance was 53.4% (95% confidence interval 46.0% to 60.8%) for ampicillin, 23.6% (13.9% to 32.3%) for trimethoprim, 8.2% (7.9% to 9.6%) for co-amoxiclav, and 2.1% (0.8 to 4.4%) for ciprofloxacin; nitrofurantoin was the lowest at 1.3% (0.8% to 1.7%). Resistance in studies in countries outside the OECD was significantly higher: 79.8% (73.0% to 87.7%) for ampicillin, 60.3% (40.9% to 79.0%) for co-amoxiclav, 26.8% (11.1% to 43.0%) for ciprofloxacin, and 17.0% (9.8% to 24.2%) for nitrofurantoin. There was evidence that bacterial isolates from the urinary tract from individual children who had received previous prescriptions for antibiotics in primary care were more likely to be resistant to antibiotics, and this increased risk could persist for up to six months (odds ratio 13.23, 95% confidence interval 7.84 to 22.31). <b>Conclusions</b> Prevalence of resistance to commonly prescribed antibiotics in primary care in children with urinary tract infections caused by <i>E coli</i> is high, particularly in countries outside the OECD, where one possible explanation is the availability of antibiotics over the counter. This could render some antibiotics ineffective as first line treatments for urinary tract infection. Routine use of antibiotics in primary care contributes to antimicrobial resistance in children, which can persist for up to six months after treatment." @default.
• W2302483558 created "2016-06-24" @default.
• W2302483558 creator A5004111593 @default.
• W2302483558 creator A5005801305 @default.
• W2302483558 creator A5016196760 @default.
• W2302483558 creator A5017634874 @default.
• W2302483558 creator A5055851820 @default.
• W2302483558 creator A5078162280 @default.
• W2302483558 date "2016-03-15" @default.
• W2302483558 modified "2023-10-17" @default.
• W2302483558 title "Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by<i>Escherichia coli</i>and association with routine use of antibiotics in primary care: systematic review and meta-analysis" @default.
• W2302483558 cites W1547919047 @default.
• W2302483558 cites W1579434614 @default.
• W2302483558 cites W1748063039 @default.
• W2302483558 cites W1765901580 @default.
• W2302483558 cites W1894147964 @default.
• W2302483558 cites W1966765690 @default.
• W2302483558 cites W1966830421 @default.
• W2302483558 cites W1969774083 @default.
• W2302483558 cites W1971635729 @default.
• W2302483558 cites W1972115023 @default.
• W2302483558 cites W1972323571 @default.
• W2302483558 cites W1979328747 @default.
• W2302483558 cites W1981419233 @default.
• W2302483558 cites W1984380244 @default.
• W2302483558 cites W1988782074 @default.
• W2302483558 cites W1988985355 @default.
• W2302483558 cites W1990405213 @default.
• W2302483558 cites W2001145363 @default.
• W2302483558 cites W2007477362 @default.
• W2302483558 cites W2013683738 @default.
• W2302483558 cites W2018379413 @default.
• W2302483558 cites W2024290767 @default.
• W2302483558 cites W2033508701 @default.
• W2302483558 cites W2033992948 @default.
• W2302483558 cites W2035622890 @default.
• W2302483558 cites W2035716162 @default.
• W2302483558 cites W2037067706 @default.
• W2302483558 cites W2037092064 @default.
• W2302483558 cites W2038559374 @default.
• W2302483558 cites W2039126739 @default.
• W2302483558 cites W2044262600 @default.
• W2302483558 cites W2044976016 @default.
• W2302483558 cites W2048515891 @default.
• W2302483558 cites W2049526639 @default.
• W2302483558 cites W2053540856 @default.
• W2302483558 cites W2054808435 @default.
• W2302483558 cites W2054880253 @default.
• W2302483558 cites W2055424701 @default.
• W2302483558 cites W2059139232 @default.
• W2302483558 cites W2060407921 @default.
• W2302483558 cites W2061463653 @default.
• W2302483558 cites W2062649635 @default.
• W2302483558 cites W2064753390 @default.
• W2302483558 cites W2068773086 @default.
• W2302483558 cites W2070450783 @default.
• W2302483558 cites W2071203374 @default.
• W2302483558 cites W2074000811 @default.
• W2302483558 cites W2076609559 @default.
• W2302483558 cites W2087594543 @default.
• W2302483558 cites W2089405582 @default.
• W2302483558 cites W2089493916 @default.
• W2302483558 cites W2093527665 @default.
• W2302483558 cites W2095686166 @default.
• W2302483558 cites W2100214388 @default.
• W2302483558 cites W2100353213 @default.
• W2302483558 cites W2112646751 @default.
• W2302483558 cites W2113664107 @default.
• W2302483558 cites W2114421984 @default.
• W2302483558 cites W2120750073 @default.
• W2302483558 cites W2122601295 @default.
• W2302483558 cites W2125837765 @default.
• W2302483558 cites W2127860269 @default.
• W2302483558 cites W2129015046 @default.
• W2302483558 cites W2129887161 @default.
• W2302483558 cites W2131208411 @default.
• W2302483558 cites W2133990749 @default.
• W2302483558 cites W2140418372 @default.
• W2302483558 cites W2143608716 @default.
• W2302483558 cites W2145065728 @default.
• W2302483558 cites W2147321550 @default.
• W2302483558 cites W2149923935 @default.
• W2302483558 cites W2153842044 @default.
• W2302483558 cites W2155247344 @default.
• W2302483558 cites W2156098321 @default.
• W2302483558 cites W2158264979 @default.
• W2302483558 cites W2158286468 @default.
• W2302483558 cites W2158662864 @default.
• W2302483558 cites W2159119281 @default.
• W2302483558 cites W2159851752 @default.
• W2302483558 cites W2161419021 @default.
• W2302483558 cites W2162584334 @default.
• W2302483558 cites W2182043732 @default.
• W2302483558 cites W2184083532 @default.
• W2302483558 cites W22834980 @default.
• W2302483558 cites W2323209472 @default.
• W2302483558 cites W2332173183 @default.
• W2302483558 cites W2468996569 @default.

• next