Matches in SemOpenAlex for { <https://semopenalex.org/work/W2304004013> ?p ?o ?g. }
- W2304004013 endingPage "314" @default.
- W2304004013 startingPage "310" @default.
- W2304004013 abstract "Eight heterocycles have been prepared in a one-pot reaction manner based on the Hantzsch dihydropyridine synthesis. The synthesis afforded seven dihydropyridines (DHP) and one unexpected 1,3-oxazin-6-one. Their structures were confirmed based on NMR spectroscopy and mass spectrometry. The obtained products have been evaluated for their cytotoxicity against eight cancer cell lines and one normal cell line. Two halogenated DHPs (7 and 8) displayed cytotoxicity toward all the nine tested cancer cell lines with IC50 values from 4.10 to 58.90 μm, while others showed selective activities. DHPs (7 and 8) bearing a Me group at C(2) and C(6) as well as a halogenated substituent at C(4′) were more antiproliferative than the others." @default.
- W2304004013 created "2016-06-24" @default.
- W2304004013 creator A5024454014 @default.
- W2304004013 creator A5026401639 @default.
- W2304004013 creator A5050551827 @default.
- W2304004013 creator A5052981792 @default.
- W2304004013 creator A5087995617 @default.
- W2304004013 date "2016-04-01" @default.
- W2304004013 modified "2023-10-16" @default.
- W2304004013 title "Synthesis and Cytotoxicity of 1,4-Dihydropyridines and an Unexpected 1,3-Oxazin-6-one" @default.
- W2304004013 cites W1991803843 @default.
- W2304004013 cites W2010068397 @default.
- W2304004013 cites W2046365384 @default.
- W2304004013 cites W2051507935 @default.
- W2304004013 cites W2057907582 @default.
- W2304004013 cites W2059915138 @default.
- W2304004013 cites W2071825833 @default.
- W2304004013 cites W2073097593 @default.
- W2304004013 cites W2075948034 @default.
- W2304004013 cites W2075983065 @default.
- W2304004013 cites W2088630040 @default.
- W2304004013 cites W2102085111 @default.
- W2304004013 cites W2105462087 @default.
- W2304004013 cites W2151028908 @default.
- W2304004013 cites W2154110619 @default.
- W2304004013 cites W2154385453 @default.
- W2304004013 cites W2160668192 @default.
- W2304004013 cites W2334465613 @default.
- W2304004013 cites W2951710732 @default.
- W2304004013 cites W2951784757 @default.
- W2304004013 doi "https://doi.org/10.1002/hlca.201500265" @default.
- W2304004013 hasPublicationYear "2016" @default.
- W2304004013 type Work @default.
- W2304004013 sameAs 2304004013 @default.
- W2304004013 citedByCount "8" @default.
- W2304004013 countsByYear W23040040132017 @default.
- W2304004013 countsByYear W23040040132018 @default.
- W2304004013 countsByYear W23040040132020 @default.
- W2304004013 countsByYear W23040040132021 @default.
- W2304004013 countsByYear W23040040132022 @default.
- W2304004013 crossrefType "journal-article" @default.
- W2304004013 hasAuthorship W2304004013A5024454014 @default.
- W2304004013 hasAuthorship W2304004013A5026401639 @default.
- W2304004013 hasAuthorship W2304004013A5050551827 @default.
- W2304004013 hasAuthorship W2304004013A5052981792 @default.
- W2304004013 hasAuthorship W2304004013A5087995617 @default.
- W2304004013 hasConcept C109316439 @default.
- W2304004013 hasConcept C121608353 @default.
- W2304004013 hasConcept C126322002 @default.
- W2304004013 hasConcept C162356407 @default.
- W2304004013 hasConcept C178790620 @default.
- W2304004013 hasConcept C185592680 @default.
- W2304004013 hasConcept C202751555 @default.
- W2304004013 hasConcept C203014093 @default.
- W2304004013 hasConcept C21951064 @default.
- W2304004013 hasConcept C2778048844 @default.
- W2304004013 hasConcept C2778371730 @default.
- W2304004013 hasConcept C2778689049 @default.
- W2304004013 hasConcept C2780866276 @default.
- W2304004013 hasConcept C2781212610 @default.
- W2304004013 hasConcept C2994372470 @default.
- W2304004013 hasConcept C43617362 @default.
- W2304004013 hasConcept C519063684 @default.
- W2304004013 hasConcept C54355233 @default.
- W2304004013 hasConcept C55493867 @default.
- W2304004013 hasConcept C66974803 @default.
- W2304004013 hasConcept C71240020 @default.
- W2304004013 hasConcept C71924100 @default.
- W2304004013 hasConcept C81885089 @default.
- W2304004013 hasConcept C86803240 @default.
- W2304004013 hasConcept C96232424 @default.
- W2304004013 hasConceptScore W2304004013C109316439 @default.
- W2304004013 hasConceptScore W2304004013C121608353 @default.
- W2304004013 hasConceptScore W2304004013C126322002 @default.
- W2304004013 hasConceptScore W2304004013C162356407 @default.
- W2304004013 hasConceptScore W2304004013C178790620 @default.
- W2304004013 hasConceptScore W2304004013C185592680 @default.
- W2304004013 hasConceptScore W2304004013C202751555 @default.
- W2304004013 hasConceptScore W2304004013C203014093 @default.
- W2304004013 hasConceptScore W2304004013C21951064 @default.
- W2304004013 hasConceptScore W2304004013C2778048844 @default.
- W2304004013 hasConceptScore W2304004013C2778371730 @default.
- W2304004013 hasConceptScore W2304004013C2778689049 @default.
- W2304004013 hasConceptScore W2304004013C2780866276 @default.
- W2304004013 hasConceptScore W2304004013C2781212610 @default.
- W2304004013 hasConceptScore W2304004013C2994372470 @default.
- W2304004013 hasConceptScore W2304004013C43617362 @default.
- W2304004013 hasConceptScore W2304004013C519063684 @default.
- W2304004013 hasConceptScore W2304004013C54355233 @default.
- W2304004013 hasConceptScore W2304004013C55493867 @default.
- W2304004013 hasConceptScore W2304004013C66974803 @default.
- W2304004013 hasConceptScore W2304004013C71240020 @default.
- W2304004013 hasConceptScore W2304004013C71924100 @default.
- W2304004013 hasConceptScore W2304004013C81885089 @default.
- W2304004013 hasConceptScore W2304004013C86803240 @default.
- W2304004013 hasConceptScore W2304004013C96232424 @default.
- W2304004013 hasIssue "4" @default.
- W2304004013 hasLocation W23040040131 @default.