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- W2305010435 abstract "2533 Objectives In this study, we evaluated the accuracy of CT-based attenuation correction (AC) under the conventional CT protocol (140 kVp, on average 50-60 keV) by comparing the SPECT image qualities of different energy of radioisotopes, 201Tl, 99mTc and 131I. Methods Using a cylindrical phantom, three different SPECT scans of 201Tl (70 keV, 1.5 mCi), 99mTc (140 keV, 7.6 mCi) and 131I (364 keV, 2.6 mCi) were performed. The CT image was obtained with 140 kVp and 2.5 mA in GE Hawkeye 4. The OSEM reconstruction algorithm was performed with 2 iterations and 10 subsets. vs. non-AC and scatter correction (SC) vs. non-SC were compared in terms of uniformity and center to peripheral ratio (CPR). Results The uniformity was calculated from the uniform whole region in the reconstructed images. For 201Tl and 99mTc, the uniformities were improved by about 10% AC was applied, but these were decreased by about 2% as SC was applied. The uniformity of 131I was slightly increased as both AC and SC were applied. The CPR in the reconstructed image was close to one when AC was applied for 201Tl and 99mTc scans, and when SC was only applied for 131I scan. Conclusions The image uniformity and CPR of 201Tl and 99mTc were affected by only AC without SC, and for 131I scan, SC more influenced the image quality than AC under the conventional CT protocol in SPECT/CT" @default.
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- W2305010435 date "2012-05-01" @default.
- W2305010435 modified "2023-09-27" @default.
- W2305010435 title "Accuracy evaluation of CT-based attenuation correction in SPECT with different energy of radioisotopes" @default.
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