FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2305994711> ?p ?o ?g. }

• W2305994711 endingPage "64" @default.
• W2305994711 startingPage "59" @default.
• W2305994711 abstract "Hyperhomocysteinemia is an independent risk factor for cardiovascular disease, but the mechanism for this risk remains unclear. While reducing serum total homocysteine (tHcy) has been shown to decrease strokes, there is no evidence for an effect on myocardial infarctions in randomized controlled trials. This study aims to examine the relationship between tHcy and several lipid measures.Our analyses included 18,297 U.S. adults from the Very Large Database of Lipids who had an extended lipid panel including direct measurement of triglycerides (TG), and the cholesterol concentration of low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), non-HDL-C, very low-density lipoprotein (VLDL-C), and remnant-lipoprotein cholesterol (RLP-C: IDL-C + VLDL3-C). Additional measurements were tHcy, hemoglobin A1c (HbA1c), insulin, creatinine, and blood urea nitrogen (BUN). Subjects were categorized into tHcy quartiles. Linear regression models were performed using lipids and tHcy as dependent and independent variables respectively, and further adjusted with age, sex, HbA1c, insulin, creatinine, and BUN levels in multivariable regression.In unadjusted analysis, levels of LDL-C (p < 0.001), non-HDL-C (p < 0.001) and HDL-C (p < 0.001) were 7-10% lower whereas levels of TG (p < 0.001), VLDL-C (p = 0.016) and RLP-C (p < 0.001) were 2-6% higher in the highest tHcy quartile. These associations between tHcy levels and lipids were eliminated (p-value range: 0.101-0.750) when controlling for age, sex, HbA1c, insulin, creatinine, and BUN.Although high levels of tHcy were associated with 2-6% higher TG-rich lipoproteins in unadjusted analysis, after adjustment for confounders our findings do not support the hypothesis that hyperhomocysteinemia is associated with an atherogenic lipid profile." @default.
• W2305994711 created "2016-06-24" @default.
• W2305994711 creator A5014267007 @default.
• W2305994711 creator A5039195997 @default.
• W2305994711 creator A5063907190 @default.
• W2305994711 creator A5071250188 @default.
• W2305994711 creator A5076662257 @default.
• W2305994711 date "2016-06-01" @default.
• W2305994711 modified "2023-10-17" @default.
• W2305994711 title "Serum homocysteine is not independently associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-21) study" @default.
• W2305994711 cites W148810285 @default.
• W2305994711 cites W1722951830 @default.
• W2305994711 cites W1892960440 @default.
• W2305994711 cites W1963662956 @default.
• W2305994711 cites W1964974907 @default.
• W2305994711 cites W1972143252 @default.
• W2305994711 cites W1972966863 @default.
• W2305994711 cites W1973462388 @default.
• W2305994711 cites W1975325821 @default.
• W2305994711 cites W1975357252 @default.
• W2305994711 cites W1982058478 @default.
• W2305994711 cites W1989589017 @default.
• W2305994711 cites W1993154381 @default.
• W2305994711 cites W1993158710 @default.
• W2305994711 cites W2006304904 @default.
• W2305994711 cites W2014398718 @default.
• W2305994711 cites W2024199357 @default.
• W2305994711 cites W2031073211 @default.
• W2305994711 cites W2031958116 @default.
• W2305994711 cites W2044024667 @default.
• W2305994711 cites W2048261560 @default.
• W2305994711 cites W2055552402 @default.
• W2305994711 cites W2062378136 @default.
• W2305994711 cites W2062881123 @default.
• W2305994711 cites W2063852510 @default.
• W2305994711 cites W2067079050 @default.
• W2305994711 cites W2077076963 @default.
• W2305994711 cites W2086084865 @default.
• W2305994711 cites W2086847901 @default.
• W2305994711 cites W2087226015 @default.
• W2305994711 cites W2090685111 @default.
• W2305994711 cites W2094744511 @default.
• W2305994711 cites W2109544293 @default.
• W2305994711 cites W2116238527 @default.
• W2305994711 cites W2123066180 @default.
• W2305994711 cites W2126013994 @default.
• W2305994711 cites W2132780908 @default.
• W2305994711 cites W2144125787 @default.
• W2305994711 cites W2146516021 @default.
• W2305994711 cites W2147583143 @default.
• W2305994711 cites W2148072012 @default.
• W2305994711 cites W2149030597 @default.
• W2305994711 cites W2150248304 @default.
• W2305994711 cites W2150352511 @default.
• W2305994711 cites W2150842829 @default.
• W2305994711 cites W2153766254 @default.
• W2305994711 cites W2158621858 @default.
• W2305994711 cites W2169022408 @default.
• W2305994711 cites W2169709289 @default.
• W2305994711 cites W233830671 @default.
• W2305994711 doi "https://doi.org/10.1016/j.atherosclerosis.2016.03.031" @default.
• W2305994711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27065242" @default.
• W2305994711 hasPublicationYear "2016" @default.
• W2305994711 type Work @default.
• W2305994711 sameAs 2305994711 @default.
• W2305994711 citedByCount "10" @default.
• W2305994711 countsByYear W23059947112017 @default.
• W2305994711 countsByYear W23059947112018 @default.
• W2305994711 countsByYear W23059947112019 @default.
• W2305994711 countsByYear W23059947112022 @default.
• W2305994711 countsByYear W23059947112023 @default.
• W2305994711 crossrefType "journal-article" @default.
• W2305994711 hasAuthorship W2305994711A5014267007 @default.
• W2305994711 hasAuthorship W2305994711A5039195997 @default.
• W2305994711 hasAuthorship W2305994711A5063907190 @default.
• W2305994711 hasAuthorship W2305994711A5071250188 @default.
• W2305994711 hasAuthorship W2305994711A5076662257 @default.
• W2305994711 hasConcept C126322002 @default.
• W2305994711 hasConcept C134018914 @default.
• W2305994711 hasConcept C139572402 @default.
• W2305994711 hasConcept C2776523773 @default.
• W2305994711 hasConcept C2777090595 @default.
• W2305994711 hasConcept C2778163477 @default.
• W2305994711 hasConcept C2778176769 @default.
• W2305994711 hasConcept C2778270857 @default.
• W2305994711 hasConcept C2780072125 @default.
• W2305994711 hasConcept C2780306776 @default.
• W2305994711 hasConcept C2780541478 @default.
• W2305994711 hasConcept C44249647 @default.
• W2305994711 hasConcept C68443243 @default.
• W2305994711 hasConcept C71924100 @default.
• W2305994711 hasConcept C8243546 @default.
• W2305994711 hasConceptScore W2305994711C126322002 @default.
• W2305994711 hasConceptScore W2305994711C134018914 @default.
• W2305994711 hasConceptScore W2305994711C139572402 @default.
• W2305994711 hasConceptScore W2305994711C2776523773 @default.
• W2305994711 hasConceptScore W2305994711C2777090595 @default.
• W2305994711 hasConceptScore W2305994711C2778163477 @default.

• next