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• W2307314426 abstract "Significance Heme-containing proteins are found in all living species and carry out a wide variety of biological functions. It is becoming clear that heme has a wider regulatory role in the cell; one such regulatory role is in control of ion channel function. In this paper, we demonstrated heme-dependent regulation of K ATP channels and identified the heme-binding location as being on a sulphonylurea receptor subunit of the channel. We use this information to present a hypothesis for how heme regulation across numerous ion channels may occur." @default.
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• W2307314426 date "2016-03-22" @default.
• W2307314426 modified "2023-10-16" @default.
• W2307314426 title "A heme-binding domain controls regulation of ATP-dependent potassium channels" @default.
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• W2307314426 doi "https://doi.org/10.1073/pnas.1600211113" @default.
• W2307314426 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4833257" @default.
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• W2307314426 hasPublicationYear "2016" @default.
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