Matches in SemOpenAlex for { <https://semopenalex.org/work/W2307589624> ?p ?o ?g. }
- W2307589624 endingPage "1" @default.
- W2307589624 startingPage "1" @default.
- W2307589624 abstract "Brain-derived neurotrophic factor (BDNF), which regulates neuronal survival, growth differentiation, and synapse formation, is known to be associated with depression and post-traumatic stress disorder (PTSD). However, the molecular mechanism for those mental disorders remains unknown. Studies have shown that BDNF is associated with PTSD risk and exaggerated startle reaction (a major arousal manifestation of PTSD) in United States military service members who were deployed during the wars in Iraq and Afghanistan. The frequency of the Met/Met in BDNF gene was greater among those with PTSD than those without PTSD. Among individuals who experienced fewer lifetime stressful events, the Met carriers have significantly higher total and startle scores on the PTSD Checklist than the Val/Val carriers. In addition, subjects with PTSD showed higher levels of BDNF in their peripheral blood plasma than the non-probable-PTSD controls. Increased BDNF levels and startle response were observed in both blood plasma and brain hippocampus by inescapable tail shock in rats. In this paper, we reviewed these data to discuss BDNF as a potential biomarker for PTSD risk and its possible roles in the onset of PTSD." @default.
- W2307589624 created "2016-06-24" @default.
- W2307589624 creator A5006117875 @default.
- W2307589624 creator A5019573704 @default.
- W2307589624 creator A5057649262 @default.
- W2307589624 date "2016-01-01" @default.
- W2307589624 modified "2023-09-23" @default.
- W2307589624 title "Post-traumatic stress disorder risk and brain-derived neurotrophic factor Val66Met" @default.
- W2307589624 cites W1484497860 @default.
- W2307589624 cites W1555679702 @default.
- W2307589624 cites W1824990411 @default.
- W2307589624 cites W1965675813 @default.
- W2307589624 cites W1967336797 @default.
- W2307589624 cites W1968595094 @default.
- W2307589624 cites W1971048191 @default.
- W2307589624 cites W1981654563 @default.
- W2307589624 cites W1981674307 @default.
- W2307589624 cites W1985955524 @default.
- W2307589624 cites W1987309900 @default.
- W2307589624 cites W1991448926 @default.
- W2307589624 cites W1994520098 @default.
- W2307589624 cites W1996038633 @default.
- W2307589624 cites W2000209446 @default.
- W2307589624 cites W2000214137 @default.
- W2307589624 cites W2008113854 @default.
- W2307589624 cites W2012423618 @default.
- W2307589624 cites W2016997563 @default.
- W2307589624 cites W2019522971 @default.
- W2307589624 cites W2020626300 @default.
- W2307589624 cites W2026770781 @default.
- W2307589624 cites W2031269976 @default.
- W2307589624 cites W2032804593 @default.
- W2307589624 cites W2037383099 @default.
- W2307589624 cites W2038372355 @default.
- W2307589624 cites W2038632822 @default.
- W2307589624 cites W2041383924 @default.
- W2307589624 cites W2051024460 @default.
- W2307589624 cites W2054386233 @default.
- W2307589624 cites W2061196406 @default.
- W2307589624 cites W2068339468 @default.
- W2307589624 cites W2078246734 @default.
- W2307589624 cites W2085694727 @default.
- W2307589624 cites W2087081892 @default.
- W2307589624 cites W2087090756 @default.
- W2307589624 cites W2092238952 @default.
- W2307589624 cites W2099136954 @default.
- W2307589624 cites W2110696099 @default.
- W2307589624 cites W2117527509 @default.
- W2307589624 cites W2122606472 @default.
- W2307589624 cites W2134083528 @default.
- W2307589624 cites W2138182618 @default.
- W2307589624 cites W2146449046 @default.
- W2307589624 cites W2147568648 @default.
- W2307589624 cites W2159759071 @default.
- W2307589624 cites W2166799435 @default.
- W2307589624 cites W2168146505 @default.
- W2307589624 cites W2320049894 @default.
- W2307589624 cites W2404639217 @default.
- W2307589624 cites W85816378 @default.
- W2307589624 doi "https://doi.org/10.5498/wjp.v6.i1.1" @default.
- W2307589624 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4804258" @default.
- W2307589624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27014593" @default.
- W2307589624 hasPublicationYear "2016" @default.
- W2307589624 type Work @default.
- W2307589624 sameAs 2307589624 @default.
- W2307589624 citedByCount "39" @default.
- W2307589624 countsByYear W23075896242016 @default.
- W2307589624 countsByYear W23075896242017 @default.
- W2307589624 countsByYear W23075896242018 @default.
- W2307589624 countsByYear W23075896242019 @default.
- W2307589624 countsByYear W23075896242020 @default.
- W2307589624 countsByYear W23075896242021 @default.
- W2307589624 countsByYear W23075896242022 @default.
- W2307589624 countsByYear W23075896242023 @default.
- W2307589624 crossrefType "journal-article" @default.
- W2307589624 hasAuthorship W2307589624A5006117875 @default.
- W2307589624 hasAuthorship W2307589624A5019573704 @default.
- W2307589624 hasAuthorship W2307589624A5057649262 @default.
- W2307589624 hasBestOaLocation W23075896241 @default.
- W2307589624 hasConcept C118552586 @default.
- W2307589624 hasConcept C126322002 @default.
- W2307589624 hasConcept C139719470 @default.
- W2307589624 hasConcept C143998085 @default.
- W2307589624 hasConcept C15744967 @default.
- W2307589624 hasConcept C160539049 @default.
- W2307589624 hasConcept C162324750 @default.
- W2307589624 hasConcept C169760540 @default.
- W2307589624 hasConcept C170493617 @default.
- W2307589624 hasConcept C2776867660 @default.
- W2307589624 hasConcept C2778159538 @default.
- W2307589624 hasConcept C2778790584 @default.
- W2307589624 hasConcept C2781161787 @default.
- W2307589624 hasConcept C36951298 @default.
- W2307589624 hasConcept C50440223 @default.
- W2307589624 hasConcept C70410870 @default.
- W2307589624 hasConcept C71924100 @default.
- W2307589624 hasConceptScore W2307589624C118552586 @default.
- W2307589624 hasConceptScore W2307589624C126322002 @default.