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- W2308131085 abstract "A simple, accurate and precise high performance thin layer chromatographic method has been developed for the estimation of Valsartan and Nebivolol hydrochloride simultaneously from a tablet dosage form. The method employed silica gel 60 F254 precoated plates as stationary phase and a mixture of Ethyl acetate: Methanol: Ammonia (6.5:2.5:0.5%v/v/v) as mobile phase. Densitometric scanning was performed at 280 nm using Camag TLC scanner 3. Beer's law was obeyed in the concentration range of 800ng/spot-2400ng/spot for Nebivolol hydrochloride and 200ng/spot1000ng/spot for Valsartan. The Retention factors for Nebivolol hydrochloride is 0.75 ± 0.04 and for Valsartan is 0.27 ± 0.01. The method was validated as per ICH Guidelines, proving its utility in estimation of Valsartan and Nebivolol hydrochloride in combined dosage form." @default.
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- W2308131085 date "2009-12-28" @default.
- W2308131085 modified "2023-09-28" @default.
- W2308131085 title "A Validated High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Nebivolol Hydrochloride and Valsartan in Pharmaceutical Dosage Form" @default.
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