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- W2308145610 abstract "Bacterial pathogens utilize a multitude of methods to invade mammalian hosts, damage tissue sites, and thwart the immune system from responding. One essential component of these strategies for many bacterial pathogens is the secretion of proteins across phospholipid membranes. Secreted proteins can play many roles in promoting bacterial virulence, from enhancing attachment to eukaryotic cells, to scavenging resources in an environmental niche, to directly intoxicating target cells and disrupting their functions. Many pathogens use dedicated protein secretion systems to secrete virulence factors from the cytosol of the bacteria into host cells or the host environment. In general, bacterial protein secretion apparatuses can be divided into classes, based on their structures, functions, and specificity. Some systems are conserved in all classes of bacteria and secrete a broad array of substrates, while others are only found in a small number of bacterial species and/or are specific to only one or a few proteins. In this chapter, we review the canonical features of several common bacterial protein secretion systems, as well as their roles in promoting the virulence of bacterial pathogens. Additionally, we address recent findings that indicate that the innate immune system of the host can detect and respond to the presence of protein secretion systems during mammalian infection." @default.
- W2308145610 created "2016-06-24" @default.
- W2308145610 creator A5004239190 @default.
- W2308145610 creator A5011242545 @default.
- W2308145610 date "2016-01-29" @default.
- W2308145610 modified "2023-10-14" @default.
- W2308145610 title "Bacterial Secretion Systems: An Overview" @default.
- W2308145610 cites W1506950787 @default.
- W2308145610 cites W1549932090 @default.
- W2308145610 cites W1550124992 @default.
- W2308145610 cites W157696361 @default.
- W2308145610 cites W1592427016 @default.
- W2308145610 cites W1646344861 @default.
- W2308145610 cites W1745018338 @default.
- W2308145610 cites W1820977051 @default.
- W2308145610 cites W1846035505 @default.
- W2308145610 cites W1855676723 @default.
- W2308145610 cites W1904782847 @default.
- W2308145610 cites W1907957509 @default.
- W2308145610 cites W1915721517 @default.
- W2308145610 cites W1918587989 @default.
- W2308145610 cites W1918908790 @default.
- W2308145610 cites W1920434477 @default.
- W2308145610 cites W1938998220 @default.
- W2308145610 cites W1963268238 @default.
- W2308145610 cites W1964467456 @default.
- W2308145610 cites W1966070420 @default.
- W2308145610 cites W1966994877 @default.
- W2308145610 cites W1967082534 @default.
- W2308145610 cites W1974471085 @default.
- W2308145610 cites W1976555793 @default.
- W2308145610 cites W1976930511 @default.
- W2308145610 cites W1980640496 @default.
- W2308145610 cites W1983311630 @default.
- W2308145610 cites W1986889683 @default.
- W2308145610 cites W1987087200 @default.
- W2308145610 cites W1987273310 @default.
- W2308145610 cites W1990657715 @default.
- W2308145610 cites W1992470956 @default.
- W2308145610 cites W1993356535 @default.
- W2308145610 cites W1993791447 @default.
- W2308145610 cites W1993796017 @default.
- W2308145610 cites W1993995188 @default.
- W2308145610 cites W1995517639 @default.
- W2308145610 cites W1998755383 @default.
- W2308145610 cites W2000994765 @default.
- W2308145610 cites W2003570753 @default.
- W2308145610 cites W2004745913 @default.
- W2308145610 cites W2006635484 @default.
- W2308145610 cites W2009587256 @default.
- W2308145610 cites W2012506575 @default.
- W2308145610 cites W2016510254 @default.
- W2308145610 cites W2017870685 @default.
- W2308145610 cites W2019288211 @default.
- W2308145610 cites W2022873862 @default.
- W2308145610 cites W2023874344 @default.
- W2308145610 cites W2026617262 @default.
- W2308145610 cites W2028819914 @default.
- W2308145610 cites W2031009429 @default.
- W2308145610 cites W2032419237 @default.
- W2308145610 cites W2034048814 @default.
- W2308145610 cites W2035295085 @default.
- W2308145610 cites W2036445018 @default.
- W2308145610 cites W2037279684 @default.
- W2308145610 cites W2038718832 @default.
- W2308145610 cites W2039817895 @default.
- W2308145610 cites W2040651284 @default.
- W2308145610 cites W2041486230 @default.
- W2308145610 cites W2044184104 @default.
- W2308145610 cites W2048199055 @default.
- W2308145610 cites W2051072617 @default.
- W2308145610 cites W2051228958 @default.
- W2308145610 cites W2052470499 @default.
- W2308145610 cites W2052569038 @default.
- W2308145610 cites W2052812619 @default.
- W2308145610 cites W2053352075 @default.
- W2308145610 cites W2054163716 @default.
- W2308145610 cites W2054963781 @default.
- W2308145610 cites W2057740405 @default.
- W2308145610 cites W2058677329 @default.
- W2308145610 cites W2061804805 @default.
- W2308145610 cites W2061856372 @default.
- W2308145610 cites W2065014293 @default.
- W2308145610 cites W2066218808 @default.
- W2308145610 cites W2066892857 @default.
- W2308145610 cites W2067360915 @default.
- W2308145610 cites W2073723461 @default.
- W2308145610 cites W2074439439 @default.
- W2308145610 cites W2076604312 @default.
- W2308145610 cites W2080147566 @default.
- W2308145610 cites W2081535038 @default.
- W2308145610 cites W2082662724 @default.
- W2308145610 cites W2083917706 @default.
- W2308145610 cites W2086993255 @default.
- W2308145610 cites W2087542083 @default.
- W2308145610 cites W2089106017 @default.
- W2308145610 cites W2089228242 @default.
- W2308145610 cites W2089594628 @default.
- W2308145610 cites W2090591880 @default.
- W2308145610 cites W2092160051 @default.