FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2308362905> ?p ?o ?g. }

• W2308362905 endingPage "1741" @default.
• W2308362905 startingPage "1736" @default.
• W2308362905 abstract "Objective To evaluate demographic data and clinical and laboratory features at disease diagnosis in 3 different age groups of childhood‐onset systemic lupus erythematosus (SLE): group A, early‐onset (<6 years); group B, school age (≥6 to <12 years); and group C, adolescent (≥12 to <18 years). Methods This was a Brazilian multicenter cohort retrospective study in 10 pediatric rheumatology centers, including 847 childhood‐onset SLE patients. Results Patients were divided into 3 groups: group A with 39 patients (4%), group B with 395 patients (47%), and group C with 413 patients (49%). Of 39 childhood‐onset SLE patients in group A, 3 (8%) were ages <2 years, 4 (10%) were ≥2 to <3 years, and 32 (82%) were ≥3 and <6 years. A total of 74 childhood‐onset SLE patients were analyzed for C1q levels, and complete C1q deficiency was observed in 3 of 74 patients (4%), all in group A. Groups were similar regarding high frequencies of female sex, nephritis, neuropsychiatric involvement, Systemic Lupus Erythematosus Disease Activity Index 2000 score ≥8, autoantibody profile, elevated acute phase proteins, and low complement levels ( P > 0.05). However, the frequency of fever (78% versus 61% versus 47%; P < 0.0001), hepatomegaly (42% versus 29% versus 14%; P < 0.0001), splenomegaly (28% versus 12% versus 4%; P < 0.0001), and discoid lupus (13% versus 4% versus 4%; P = 0.020) was significantly higher in group A compared to groups B and C. The frequency of weight loss >2 kg (19% versus 28% versus 36%; P = 0.017), photosensitivity (34% versus 41% versus 51%; P = 0.006), leukopenia <4,000/mm 3 (14% versus 25% versus 30%; P = 0.048), and lymphopenia <1,500/mm 3 (22% versus 41% versus 47%; P = 0.011) was significantly lower in group A. Conclusion Our large multicenter study identified the finding that the initial appearance of childhood‐onset SLE is characterized by comparable high frequency of internal organ involvement and some distinct clinical and laboratory features in early‐onset and adolescent groups." @default.
• W2308362905 created "2016-06-24" @default.
• W2308362905 creator A5004618380 @default.
• W2308362905 creator A5006209293 @default.
• W2308362905 creator A5013263137 @default.
• W2308362905 creator A5015977988 @default.
• W2308362905 creator A5018309357 @default.
• W2308362905 creator A5034207260 @default.
• W2308362905 creator A5061052463 @default.
• W2308362905 creator A5065178869 @default.
• W2308362905 creator A5067610116 @default.
• W2308362905 creator A5079354971 @default.
• W2308362905 creator A5081638079 @default.
• W2308362905 creator A5085211757 @default.
• W2308362905 creator A5089162243 @default.
• W2308362905 creator A5091260974 @default.
• W2308362905 date "2016-10-06" @default.
• W2308362905 modified "2023-10-17" @default.
• W2308362905 title "Features of 847 Childhood-Onset Systemic Lupus Erythematosus Patients in Three Age Groups at Diagnosis: A Brazilian Multicenter Study" @default.
• W2308362905 cites W1973376137 @default.
• W2308362905 cites W1973914566 @default.
• W2308362905 cites W1975743269 @default.
• W2308362905 cites W1987604922 @default.
• W2308362905 cites W2014826835 @default.
• W2308362905 cites W2017292568 @default.
• W2308362905 cites W2038511894 @default.
• W2308362905 cites W2040552793 @default.
• W2308362905 cites W2043109729 @default.
• W2308362905 cites W2047145342 @default.
• W2308362905 cites W2070527591 @default.
• W2308362905 cites W2086801282 @default.
• W2308362905 cites W2119593936 @default.
• W2308362905 cites W2121914099 @default.
• W2308362905 cites W2139852903 @default.
• W2308362905 cites W2162899682 @default.
• W2308362905 cites W2166232173 @default.
• W2308362905 cites W2171406118 @default.
• W2308362905 cites W2561536790 @default.
• W2308362905 cites W4251458288 @default.
• W2308362905 cites W4296981399 @default.
• W2308362905 doi "https://doi.org/10.1002/acr.22881" @default.
• W2308362905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27014968" @default.
• W2308362905 hasPublicationYear "2016" @default.
• W2308362905 type Work @default.
• W2308362905 sameAs 2308362905 @default.
• W2308362905 citedByCount "45" @default.
• W2308362905 countsByYear W23083629052016 @default.
• W2308362905 countsByYear W23083629052017 @default.
• W2308362905 countsByYear W23083629052018 @default.
• W2308362905 countsByYear W23083629052019 @default.
• W2308362905 countsByYear W23083629052020 @default.
• W2308362905 countsByYear W23083629052021 @default.
• W2308362905 countsByYear W23083629052022 @default.
• W2308362905 countsByYear W23083629052023 @default.
• W2308362905 crossrefType "journal-article" @default.
• W2308362905 hasAuthorship W2308362905A5004618380 @default.
• W2308362905 hasAuthorship W2308362905A5006209293 @default.
• W2308362905 hasAuthorship W2308362905A5013263137 @default.
• W2308362905 hasAuthorship W2308362905A5015977988 @default.
• W2308362905 hasAuthorship W2308362905A5018309357 @default.
• W2308362905 hasAuthorship W2308362905A5034207260 @default.
• W2308362905 hasAuthorship W2308362905A5061052463 @default.
• W2308362905 hasAuthorship W2308362905A5065178869 @default.
• W2308362905 hasAuthorship W2308362905A5067610116 @default.
• W2308362905 hasAuthorship W2308362905A5079354971 @default.
• W2308362905 hasAuthorship W2308362905A5081638079 @default.
• W2308362905 hasAuthorship W2308362905A5085211757 @default.
• W2308362905 hasAuthorship W2308362905A5089162243 @default.
• W2308362905 hasAuthorship W2308362905A5091260974 @default.
• W2308362905 hasBestOaLocation W23083629051 @default.
• W2308362905 hasConcept C126322002 @default.
• W2308362905 hasConcept C167135981 @default.
• W2308362905 hasConcept C187212893 @default.
• W2308362905 hasConcept C198451711 @default.
• W2308362905 hasConcept C2776670291 @default.
• W2308362905 hasConcept C2776912625 @default.
• W2308362905 hasConcept C2777785397 @default.
• W2308362905 hasConcept C2779075594 @default.
• W2308362905 hasConcept C2779134260 @default.
• W2308362905 hasConcept C2779912601 @default.
• W2308362905 hasConcept C71924100 @default.
• W2308362905 hasConcept C72563966 @default.
• W2308362905 hasConcept C90924648 @default.
• W2308362905 hasConceptScore W2308362905C126322002 @default.
• W2308362905 hasConceptScore W2308362905C167135981 @default.
• W2308362905 hasConceptScore W2308362905C187212893 @default.
• W2308362905 hasConceptScore W2308362905C198451711 @default.
• W2308362905 hasConceptScore W2308362905C2776670291 @default.
• W2308362905 hasConceptScore W2308362905C2776912625 @default.
• W2308362905 hasConceptScore W2308362905C2777785397 @default.
• W2308362905 hasConceptScore W2308362905C2779075594 @default.
• W2308362905 hasConceptScore W2308362905C2779134260 @default.
• W2308362905 hasConceptScore W2308362905C2779912601 @default.
• W2308362905 hasConceptScore W2308362905C71924100 @default.
• W2308362905 hasConceptScore W2308362905C72563966 @default.
• W2308362905 hasConceptScore W2308362905C90924648 @default.
• W2308362905 hasFunder F4320322025 @default.
• W2308362905 hasIssue "11" @default.

• next