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- W2308379698 abstract "So far the reason for persistent developmental stuttering is still unclear. Typically the speech disorder starts in preschool age. Approximately 1% of adults are stuttering. One of the aims of this study was it to investigate the lateralization of speech function. 17 adults who stutter (AWS) and 20 controls were matched for age and underwent functional magnetic resonance imaging (fMRI). The individual speech areas and the speech lateralization were investigated using single-word-paradigm also a sentence-paradigm. To investigate the functional speech lateralization we calculated a lateralization index (LI) for each speech area (Broca‘s and Wernicke’s area) and separately for each paradigm. Subsequently the fractional anisotropy (FA) in the white matter adjacent to the speech areas was measured and used for calculating an Asymmetry index (AI). In comparison to the controls the group of the AWS showed a shift in the LIs which was not significant. The reason for the shift of the LI is still unexplained. An enhanced activation in the right hemisphere of the brain of the AWS might explain these results. The protocol used it is not able to answer this question definitely. Earlier PET or fMRI studies have reported a different activation in subjects who stutter concerning parts of the motor cortex as well an atypical speech lateralization. In addition we detected a morphological difference in the subgroup of the subject of severe stuttering. We found a decrease of the asymmetry in comparison to the controls in particular adjacent to Wernicke’s area. Earlier studies showed morphological differences in AWS too. In contrast to earlier studies we focused on the individual variation of the speech areas." @default.
- W2308379698 created "2016-06-24" @default.
- W2308379698 creator A5019073195 @default.
- W2308379698 date "2022-02-20" @default.
- W2308379698 modified "2023-10-01" @default.
- W2308379698 title "Sprachlateralisierung bei Patienten mit idiopathischem Stottern und bei gesunden Probanden: Ein Vergleich der Ergebnisse funktioneller Magnetresonanztomografie mit denen der Diffusionstensorbildgebung" @default.
- W2308379698 doi "https://doi.org/10.53846/goediss-4195" @default.
- W2308379698 hasPublicationYear "2022" @default.
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