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- W2308389558 endingPage "338" @default.
- W2308389558 startingPage "329" @default.
- W2308389558 abstract "Accumulated evidence obtained from various clinical trials and animal studies suggested that cancer vaccines need better adjuvants than those that are currently licensed, which include the most commonly used alum and incomplete Freund’s adjuvant, because of either a lack of potent anti-tumor immunity or the induction of undesired immunity. Several clinical trials using immunostimulatory adjuvants, particularly agonistic as well as non-agonistic ligands for TLRs, C-type lectin receptors, retinoic acid-inducible gene I-like receptors and stimulator of interferon genes, have revealed their therapeutic potential not only as vaccine adjuvants but also as anti-tumor agents. Recently, combinations of such immunostimulatory or immunomodulatory adjuvants have shown superior efficacy over their singular use, suggesting that seeking optimal combinations of the currently available or well-characterized adjuvants may provide a better chance for the development of novel adjuvants for cancer immunotherapy." @default.
- W2308389558 created "2016-06-24" @default.
- W2308389558 creator A5013035098 @default.
- W2308389558 creator A5057735595 @default.
- W2308389558 creator A5063767722 @default.
- W2308389558 date "2016-03-22" @default.
- W2308389558 modified "2023-10-18" @default.
- W2308389558 title "Vaccine adjuvants as potential cancer immunotherapeutics" @default.
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