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- W2308472814 abstract "This study aimed at comparing aerosol deposition onto lungs using an ultrasonic (US) nebulizer, with and without using a positive end expiratory pressure (PEEP) valve, also comparing two valve pressures, 5 cmH 2 O and 10 cmH 2 O. Twelve young healthy volunteers were submitted to Tc99m radioaerosol inhalation generated by US nebulizer in three stages: without PEEP (control) and with PEEP of 5 cmH 2 O and of 10 cmH 2 O. In order to analyse aerosol deposition, regions of interest (ROI) were outlined in both lungs, each subdivided into central, intermediate, and peripheral regions; the number of Tc99m deposited particles was counted in each ROI. Data were statistically analysed. Aerosol deposition was higher when using the PEEP valve attached to the nebulizer. In both lungs, deposition when using PEEP was higher in central (p=0,012) and intermediate (p=0,01) regions. In the peripheral regions a difference was found between lungs. Comparison between pressure levels did not show any statistical significance. Data suggest that the use of PEEP valve associated to US nebulizer may increase aerosol deposition, thus improving therapeutic inhalation." @default.
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- W2308472814 date "2007-01-01" @default.
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- W2308472814 title "Associação da pressão positiva expiratória ao final da expiração ao nebulizador ultrassônico: efeito na deposição de aerossol no pulmão Association of positive end expiratory pressure to ultrasonic nebulizer: effect on aerosol deposition onto lungs" @default.
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