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- W2308493704 abstract "This study investigates the prevalence of intestinal parasitic infections in different groups of people in Jakarta Indonesia to evaluate their acceptance of an anthelmintic drug trial and to evaluate the efficacy of mebendazole in the treatment of polyparasitism. 6 groups were included: 1) 30 children of policemen aged 1-13 2) laboratory technicians and their families 3) 62 unskilled laborers and their families 4) 87 children and adults from urban and semi-urban areas and seen at private clinics 5) 51 medical students from the University of Trisakti 6) 108 school children and teachers from a rural school. Mebendazole in 100 mg tablets were given in various dosages for various parasites; no individual received more than 2 courses of treatment. 69% of the individuals had helminthic infections with 153 having evidence of 1 worm 127 with 2 and 58 with 3. Acceptance of mebendazole was good except by individuals in group 6 and it was found to be a highly effective anthelmintic. 1 dose of 100 mg was shown to cure 94% of the A. lumbricoides and 98% of O. vermicularis infections. In dosages of 2 x 100 mg for 3 days 85% of the hookworm infections and 77% of the T. trichiura infections were eliminated. After 1 course the efficacy of mebendazole against hookworm was 85% 100% after 2 courses; no effect was seen on the protozoan infections at the dosage levels used. Mebendazole is shown to be a slowacting broad spectrum anthelmintic with high efficacy against most of the common intestinal nematodes and with inhibiting action against larval development in the post-treatment excreted eggs. Erratic ascariasis was seen in 3 people but no other side effects were observed." @default.
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- W2308493704 date "1974-06-01" @default.
- W2308493704 modified "2023-09-23" @default.
- W2308493704 title "The use of mebendazole in the treatment of polyparasitism." @default.
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