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- W2308579969 abstract "article i nfo Article history: Received 10 May 2010 Received in revised form 7 February 2011 Accepted 8 February 2011 Measures of acoustic startle such as prepulse inhibition (PPI) and startle latency have been found to be impaired in schizophrenia, and are commonly thought to be related to cognitive deficits in this disease. However, findings about the relationship between startle variables and cognitive performance have been equivocal. In this study, we examined correlations between startle measures (baseline startle magnitude, latency, habituation and PPI) and cognitive performance (using the Benton Visual Retention Test, Conner's Continuous Performance Test, California Verbal Learning Test, Finger Tapping Test, and Wisconsin Card Sort Test) in 107 schizophrenia patients and 94 healthy controls. Overall, there was a lack of any significant relationship between these constructs in both populations when correcting for multiple comparisons. This suggests that alterations in startle measures seen in schizophrenia may not reflect elements of information processing that cause cognitive deficits in the disease. Published by Elsevier Ireland Ltd." @default.
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- W2308579969 date "2011-07-29" @default.
- W2308579969 modified "2023-09-27" @default.
- W2308579969 title "Lack of relationship between acoustic startle and cognitive variables in schizophrenia and control subjects" @default.
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- W2308579969 doi "https://doi.org/10.7490/f1000research.1830.1" @default.
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