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- W2308584732 abstract "Research has shown specific soy ingredients can elicit anti-diabetic actions, namely an improvement in glucose tolerance and attenuation of dyslipidemia, fatty liver and other metabolic abnormalities. The current study explored the effects of two soy-based diets on the diabetic phenotype in a porcine model. The two experimental diets were high in soybean meal and were matched for macronutrients. In the first soy-based diet (Low-Isoflavone) the meal had the isoflavones removed through an alcohol-wash extraction process and the other diet (High-Isoflavone) contained the soy isoflavones. This 3-month study was conducted on intact male boars (n = 20) at the University Swine Center. Body weight, platelet aggregation, serum lipids and glucose were assessed at the end of the study. The body weight of the High-Isoflavone group was significantly greater vs. the Low-Isoflavone group. The rate of platelet aggregation in the Low-Isoflavone group was significantly higher than the High-Isoflavone group. The Low-Isoflavone group also had significantly higher cholesterol and triglyceride levels vs. the High-Isoflavone group. There was no significant difference in fasting blood glucose between the groups. Overall, this research suggests that isoflavone containing soy-based diets may have therapeutic potential in treating some of the anomalies associated with the diabetic phenotype." @default.
- W2308584732 created "2016-06-24" @default.
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- W2308584732 date "2009-04-01" @default.
- W2308584732 modified "2023-09-26" @default.
- W2308584732 title "THE EFFECT OF VARIOUS SOY‐BASED DIETS ON THE DIABETIC PHENOTYPE IN A PORCINE MODEL" @default.
- W2308584732 doi "https://doi.org/10.1096/fasebj.23.1_supplement.924.4" @default.
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