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• W2308793883 abstract "Aim: Based on the traditional and scientific claims of intra - dermal antiplasmodial activity of bee stings, its effect on liver and serum enzymes in Plasmodium berghei - infected mice were investigated. Methodology: Twenty albino mice were intra - peritoneally infected with P. berghei and divided into four animals per group. Group I was set up as negative control (parasitized untreated), group II as parasitized treated with 5 mg chloroquine/kg body weight, group III as suppressive treated, group IV as curative treated and group five as not parasitized not treated. Results: The results of serum alanine transaminase (ALT) and aspartate transaminase (AST) of the infected treated with chloroquine shows significant increase when compared to other experimental groups (p ˂ 0.05). Whereas, there was increase in liver AST in group II, group III and group IV when compared to not parasitized not treated (p ˂ 0.05). Also, there was signific ant decrease in liver ALT activity in all the experimental groups. The serum and liver gamma glutamyl transferase (GGT) showed no significant difference (p<0.05) in the curative and suppressive groups when compared to the standard drug (chloroquine). Where as, parasitized not treated group shows significant increase (p<0.05) in the liver GGT and ALP when compared with other experimental groups. Therefore," @default.
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• W2308793883 date "2015-01-01" @default.
• W2308793883 modified "2023-09-23" @default.
• W2308793883 title "Toxicological Evaluation of Bee Sting in Plasmodium berghei Infected Mice" @default.
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