Matches in SemOpenAlex for { <https://semopenalex.org/work/W2309615146> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2309615146 endingPage "769" @default.
- W2309615146 startingPage "763" @default.
- W2309615146 abstract "Lipid peroxidation was measured by the thio-barbituric assay for malondialdehyde (MDA). A small amount of MDA was formed when medial cells from guinea pig aorta were grown in tissue culture. The polyunsaturated fatty acids 8,11,14-eicosatrienoic acid, 5,8,11,14-eicosatetraenoic acid, and 7,10,13,16-docosatetraenoic acid generated significant amounts of MDA in a time-dependent manner when they were added to cultures of medial cells and fibroblasts. MDA or its precursor remained within the cell and did not accumulate in the media. Indomethacin enhanced MDA formation from polyunsaturated fatty acid. Alpha-Tocopherol, alpha-tocopherolquinone, and 2,6-di-tert-butyl-4-methylphenol (BHT) inhibited MDA formation when a polyunsaturated fatty acid was incubated with the pro-oxidant cumene hydroperoxide. Menadione had no effect on MDA formation in the cumene hydroperoxide system. Alpha-Tocopherol and alpha-tocopherolquinone inhibited MDA formation when they were added to cells in culture. Menadione had no effect on MDA formation in tissue culture. Anti-oxidant effects which were time-dependent showed that intracellular MDA was generated from a lipid peroxide precursor during the thiobarbituric acid assay. Relative plating efficiency was measured in medial cells and fibroblasts. Alpha-Tocopherolquinone and alpha-tocopherol enhanced the extent of cell proliferation. Alpha-Tocopherolquinone overcame the inhibitory effect of a polyunsaturated fatty acid on the extent of cell proliferation. Menadione was cytotoxic. Thus antioxidant data support the hypothesis that the extent of cell proliferation is controlled in part by lipid peroxidation." @default.
- W2309615146 created "2016-06-24" @default.
- W2309615146 creator A5016022667 @default.
- W2309615146 creator A5019253126 @default.
- W2309615146 creator A5041598057 @default.
- W2309615146 creator A5080830912 @default.
- W2309615146 creator A5085918918 @default.
- W2309615146 date "1981-07-01" @default.
- W2309615146 modified "2023-10-03" @default.
- W2309615146 title "Effect of polyunsaturated fatty acids and antioxidants on lipid peroxidation in tissue cultures." @default.
- W2309615146 cites W1548078249 @default.
- W2309615146 cites W1568565787 @default.
- W2309615146 cites W1590457525 @default.
- W2309615146 cites W168049917 @default.
- W2309615146 cites W180965172 @default.
- W2309615146 cites W183744129 @default.
- W2309615146 cites W1994175131 @default.
- W2309615146 cites W2000013500 @default.
- W2309615146 cites W2001931771 @default.
- W2309615146 cites W2011282129 @default.
- W2309615146 cites W2019249025 @default.
- W2309615146 cites W2044132492 @default.
- W2309615146 cites W2047358953 @default.
- W2309615146 cites W2049466131 @default.
- W2309615146 cites W2054565838 @default.
- W2309615146 cites W2055666785 @default.
- W2309615146 cites W2077407101 @default.
- W2309615146 cites W2147267501 @default.
- W2309615146 cites W2189155100 @default.
- W2309615146 cites W2324933256 @default.
- W2309615146 cites W3165604629 @default.
- W2309615146 cites W349665183 @default.
- W2309615146 cites W420418104 @default.
- W2309615146 doi "https://doi.org/10.1016/s0022-2275(20)37347-8" @default.
- W2309615146 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7288284" @default.
- W2309615146 hasPublicationYear "1981" @default.
- W2309615146 type Work @default.
- W2309615146 sameAs 2309615146 @default.
- W2309615146 citedByCount "217" @default.
- W2309615146 countsByYear W23096151462012 @default.
- W2309615146 countsByYear W23096151462013 @default.
- W2309615146 countsByYear W23096151462014 @default.
- W2309615146 countsByYear W23096151462015 @default.
- W2309615146 countsByYear W23096151462016 @default.
- W2309615146 countsByYear W23096151462017 @default.
- W2309615146 countsByYear W23096151462018 @default.
- W2309615146 countsByYear W23096151462019 @default.
- W2309615146 countsByYear W23096151462020 @default.
- W2309615146 countsByYear W23096151462021 @default.
- W2309615146 countsByYear W23096151462022 @default.
- W2309615146 countsByYear W23096151462023 @default.
- W2309615146 crossrefType "journal-article" @default.
- W2309615146 hasAuthorship W2309615146A5016022667 @default.
- W2309615146 hasAuthorship W2309615146A5019253126 @default.
- W2309615146 hasAuthorship W2309615146A5041598057 @default.
- W2309615146 hasAuthorship W2309615146A5080830912 @default.
- W2309615146 hasAuthorship W2309615146A5085918918 @default.
- W2309615146 hasBestOaLocation W23096151461 @default.
- W2309615146 hasConcept C185592680 @default.
- W2309615146 hasConcept C19038510 @default.
- W2309615146 hasConcept C2778004101 @default.
- W2309615146 hasConcept C2780829032 @default.
- W2309615146 hasConcept C31903555 @default.
- W2309615146 hasConcept C543025807 @default.
- W2309615146 hasConcept C55493867 @default.
- W2309615146 hasConceptScore W2309615146C185592680 @default.
- W2309615146 hasConceptScore W2309615146C19038510 @default.
- W2309615146 hasConceptScore W2309615146C2778004101 @default.
- W2309615146 hasConceptScore W2309615146C2780829032 @default.
- W2309615146 hasConceptScore W2309615146C31903555 @default.
- W2309615146 hasConceptScore W2309615146C543025807 @default.
- W2309615146 hasConceptScore W2309615146C55493867 @default.
- W2309615146 hasIssue "5" @default.
- W2309615146 hasLocation W23096151461 @default.
- W2309615146 hasOpenAccess W2309615146 @default.
- W2309615146 hasPrimaryLocation W23096151461 @default.
- W2309615146 hasRelatedWork W1518810095 @default.
- W2309615146 hasRelatedWork W1964859215 @default.
- W2309615146 hasRelatedWork W2048473328 @default.
- W2309615146 hasRelatedWork W2152342291 @default.
- W2309615146 hasRelatedWork W2415317498 @default.
- W2309615146 hasRelatedWork W2472522869 @default.
- W2309615146 hasRelatedWork W2563350429 @default.
- W2309615146 hasRelatedWork W3168967012 @default.
- W2309615146 hasRelatedWork W4225746642 @default.
- W2309615146 hasRelatedWork W4323312905 @default.
- W2309615146 hasVolume "22" @default.
- W2309615146 isParatext "false" @default.
- W2309615146 isRetracted "false" @default.
- W2309615146 magId "2309615146" @default.
- W2309615146 workType "article" @default.