FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2309771944> ?p ?o ?g. }

• W2309771944 endingPage "1752" @default.
• W2309771944 startingPage "1734" @default.
• W2309771944 abstract "Delays in gene networks result from the sequential nature of protein assembly. However, it is unclear how models of gene networks that use delays should be modified when considering time-dependent changes in temperature. This is important, as delay is often used in models of genetic oscillators that can be entrained by periodic fluctuations in temperature. Here, we analytically derive the time dependence of delay distributions in response to time-varying temperature changes. We find that the resulting time-varying delay is nonlinearly dependent on parameters of the time-varying temperature such as amplitude and frequency, therefore, applying an Arrhenius scaling may result in erroneous conclusions. We use these results to examine a model of a synthetic gene oscillator with temperature compensation. We show that temperature entrainment follows from the same mechanism that results in temperature compensation. Under a common Arrhenius scaling alone, the frequency of the oscillator is sensitive to changes in the mean temperature but robust to changes in the frequency of a periodically time-varying temperature. When a mechanism for temperature compensation is included in the model, however, we show that the oscillator is entrained by periodically varying temperature even when maintaining insensitivity to the mean temperature." @default.
• W2309771944 created "2016-06-24" @default.
• W2309771944 creator A5053287366 @default.
• W2309771944 creator A5055901264 @default.
• W2309771944 creator A5080477542 @default.
• W2309771944 date "2016-01-01" @default.
• W2309771944 modified "2023-09-25" @default.
• W2309771944 title "The Effects of Time-Varying Temperature on Delays in Genetic Networks" @default.
• W2309771944 cites W158017736 @default.
• W2309771944 cites W1634905938 @default.
• W2309771944 cites W1917287361 @default.
• W2309771944 cites W1946177469 @default.
• W2309771944 cites W1969101909 @default.
• W2309771944 cites W1971117553 @default.
• W2309771944 cites W1981862895 @default.
• W2309771944 cites W1985791177 @default.
• W2309771944 cites W2003417733 @default.
• W2309771944 cites W2004734995 @default.
• W2309771944 cites W2007334358 @default.
• W2309771944 cites W2013478517 @default.
• W2309771944 cites W2016517222 @default.
• W2309771944 cites W2020191911 @default.
• W2309771944 cites W2022103697 @default.
• W2309771944 cites W2028563901 @default.
• W2309771944 cites W2037132001 @default.
• W2309771944 cites W2047279254 @default.
• W2309771944 cites W2054591837 @default.
• W2309771944 cites W2054665436 @default.
• W2309771944 cites W2058131374 @default.
• W2309771944 cites W2058366990 @default.
• W2309771944 cites W2060660326 @default.
• W2309771944 cites W2066440682 @default.
• W2309771944 cites W2068784631 @default.
• W2309771944 cites W2076240753 @default.
• W2309771944 cites W2080012312 @default.
• W2309771944 cites W2085816553 @default.
• W2309771944 cites W2088907143 @default.
• W2309771944 cites W2089558844 @default.
• W2309771944 cites W2092227167 @default.
• W2309771944 cites W2112215450 @default.
• W2309771944 cites W2114228460 @default.
• W2309771944 cites W2134459671 @default.
• W2309771944 cites W2142484802 @default.
• W2309771944 cites W2149665977 @default.
• W2309771944 cites W2153339784 @default.
• W2309771944 cites W2155418451 @default.
• W2309771944 cites W2159165793 @default.
• W2309771944 cites W2165580893 @default.
• W2309771944 cites W2166853229 @default.
• W2309771944 cites W3098928821 @default.
• W2309771944 doi "https://doi.org/10.1137/15m1040979" @default.
• W2309771944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5656297" @default.
• W2309771944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29081723" @default.
• W2309771944 hasPublicationYear "2016" @default.
• W2309771944 type Work @default.
• W2309771944 sameAs 2309771944 @default.
• W2309771944 citedByCount "11" @default.
• W2309771944 countsByYear W23097719442018 @default.
• W2309771944 countsByYear W23097719442019 @default.
• W2309771944 countsByYear W23097719442020 @default.
• W2309771944 countsByYear W23097719442021 @default.
• W2309771944 countsByYear W23097719442022 @default.
• W2309771944 crossrefType "journal-article" @default.
• W2309771944 hasAuthorship W2309771944A5053287366 @default.
• W2309771944 hasAuthorship W2309771944A5055901264 @default.
• W2309771944 hasAuthorship W2309771944A5080477542 @default.
• W2309771944 hasBestOaLocation W23097719442 @default.
• W2309771944 hasConcept C11171543 @default.
• W2309771944 hasConcept C121332964 @default.
• W2309771944 hasConcept C121864883 @default.
• W2309771944 hasConcept C135343436 @default.
• W2309771944 hasConcept C13565188 @default.
• W2309771944 hasConcept C139992725 @default.
• W2309771944 hasConcept C148898269 @default.
• W2309771944 hasConcept C154945302 @default.
• W2309771944 hasConcept C15744967 @default.
• W2309771944 hasConcept C180205008 @default.
• W2309771944 hasConcept C24890656 @default.
• W2309771944 hasConcept C2524010 @default.
• W2309771944 hasConcept C2775924081 @default.
• W2309771944 hasConcept C2780023022 @default.
• W2309771944 hasConcept C33923547 @default.
• W2309771944 hasConcept C41008148 @default.
• W2309771944 hasConcept C47446073 @default.
• W2309771944 hasConcept C4839761 @default.
• W2309771944 hasConcept C62520636 @default.
• W2309771944 hasConcept C74650414 @default.
• W2309771944 hasConcept C86183883 @default.
• W2309771944 hasConcept C99844830 @default.
• W2309771944 hasConceptScore W2309771944C11171543 @default.
• W2309771944 hasConceptScore W2309771944C121332964 @default.
• W2309771944 hasConceptScore W2309771944C121864883 @default.
• W2309771944 hasConceptScore W2309771944C135343436 @default.
• W2309771944 hasConceptScore W2309771944C13565188 @default.
• W2309771944 hasConceptScore W2309771944C139992725 @default.
• W2309771944 hasConceptScore W2309771944C148898269 @default.
• W2309771944 hasConceptScore W2309771944C154945302 @default.
• W2309771944 hasConceptScore W2309771944C15744967 @default.

• next